KEGG   ENZYME: 1.14.13.36Help
Entry
EC 1.14.13.36               Enzyme                                 

Name
5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase;
5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase;
coumaroylquinate(coumaroylshikimate) 3'-monooxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
trans-5-O-(4-coumaroyl)-D-quinate,NADPH:oxygen oxidoreductase (3'-hydroxylating)
Reaction(IUBMB)
trans-5-O-(4-coumaroyl)-D-quinate + NADPH + H+ + O2 = trans-5-O-caffeoyl-D-quinate + NADP+ + H2O [RN:R04342]
Reaction(KEGG)
R04342;
(other) R06582
Show
Substrate
trans-5-O-(4-coumaroyl)-D-quinate [CPD:C12208];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
trans-5-O-caffeoyl-D-quinate [CPD:C00852];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Comment
Also acts on trans-5-O-(4-coumaroyl)shikimate.
History
EC 1.14.13.36 created 1990
Pathway
Phenylpropanoid biosynthesis
Flavonoid biosynthesis
Stilbenoid, diarylheptanoid and gingerol biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K09754  
coumaroylquinate(coumaroylshikimate) 3'-monooxygenase
Genes
ATH: 
AT2G40890(CYP98A3)
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
105782306 105786247
EGR: 
104443731 104443755 104454510
GMX: 
100811080 606506(CYP98A2)
PVU: 
PHAVU_001G117900g
VRA: 
106753926
VAR: 
108346061
CAM: 
101502624
ADU: 
107494128
AIP: 
107604697
LJA: 
Lj1g3v4081860.1(Lj1g3v4081860.1)
LANG: 
109326958
FVE: 
101310387
PMUM: 
103319005 103319006 103319007 103344449
MDM: 
103402429 103411054 103425389 103428961 103431803 103441965
PXB: 
103944996 103944997 103944999 103946365 103946366
CSV: 
101217257
CMO: 
103486874
RCU: 
8277408 8277879 8277880
JCU: 
105636120
POP: 
POPTR_0006s03180g(POPTRDRAFT_685839) POPTR_0016s03080g POPTR_0016s03090g(POPTRDRAFT_576112)
VVI: 
100263633
SLY: 
101246092 101247849 101261765 101262063 101262367
SPEN: 
107001769 107001863 107002593 107008188 107028331
SOT: 
102578406 102578747 102585799 102586130 102590105 102590484 102590830 102590870 102593896 102603170 102606401 107059425
INI: 
109159148
SIND: 
105162700 105172202
BVG: 
104887604 104889547 104889649 104889748
NNU: 
104588272
OSA: 
4339188
DOSA: 
Os05t0494000-01(Os05g0494000) Os10t0196100-00(Os10g0196100)
OBR: 
102712257
BDI: 
100835531
ATS: 
F775_19165 F775_21689 F775_21690 F775_27986
SBI: 
SORBI_03g037380(SORBIDRAFT_03g037380) SORBI_09g024210(SORBIDRAFT_09g024210)
ZMA: 
100191539 100274274 103649031
SITA: 
101771055
PDA: 
103705056 103706282
EGU: 
105033349 105033350 105052441
MUS: 
103995155
ATR: 
18427105 18441256
SMO: 
SELMODRAFT_104330 SELMODRAFT_450942(C3'H1-1) SELMODRAFT_450943(C3'H1-2)
PPP: 
PHYPADRAFT_98753
 » show all
Taxonomy
Reference
1  [PMID:2821918]
  Authors
Kuhnl T, Koch U, Heller W, Wellmann E.
  Title
Chlorogenic acid biosynthesis: characterization of a light-induced microsomal 5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase from carrot (Daucus carota L.) cell suspension cultures.
  Journal
Arch. Biochem. Biophys. 258 (1987) 226-32.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
112131-08-5
DBGET integrated database retrieval system