KEGG   ENZYME: 1.14.13.36Help
Entry
EC 1.14.13.36               Enzyme                                 

Name
5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase;
5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase;
coumaroylquinate(coumaroylshikimate) 3'-monooxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
trans-5-O-(4-coumaroyl)-D-quinate,NADPH:oxygen oxidoreductase (3'-hydroxylating)
Reaction(IUBMB)
trans-5-O-(4-coumaroyl)-D-quinate + NADPH + H+ + O2 = trans-5-O-caffeoyl-D-quinate + NADP+ + H2O [RN:R04342]
Reaction(KEGG)
R04342;
(other) R06582
Show
Substrate
trans-5-O-(4-coumaroyl)-D-quinate [CPD:C12208];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
trans-5-O-caffeoyl-D-quinate [CPD:C00852];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Comment
Also acts on trans-5-O-(4-coumaroyl)shikimate.
History
EC 1.14.13.36 created 1990
Pathway
ec00940  Phenylpropanoid biosynthesis
ec00941  Flavonoid biosynthesis
ec00945  Stilbenoid, diarylheptanoid and gingerol biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K09754  coumaroylquinate(coumaroylshikimate) 3'-monooxygenase
Genes
RSS: 109440930
ATH: AT2G40890(CYP98A3)
ALY: ARALYDRAFT_903389
CSAT: 104782574 104785308 104792955
EUS: EUTSA_v10016538mg EUTSA_v10017706mg
BRP: 103857960 103865848 103866522
BNA: 106352767 106386334 106391625 106395719 106431114 106438010 106454525
BOE: 106335822 106340718 106342398
THJ: 104803227
CPAP: 110811301
CIT: 102624231
CIC: CICLE_v10000848mg CICLE_v10003647mg CICLE_v10011520mg CICLE_v10019813mg
TCC: 18598608
GRA: 105782306 105786247
GHI: 107920919 107935532 107950342
DZI: 111293639
EGR: 104443731 104443755 104454510
GMX: 100811080 606506(CYP98A2)
PVU: PHAVU_001G117900g
VRA: 106753926
VAR: 108346061
CCAJ: 109802555
CAM: 101502624
ADU: 107494128
AIP: 107604697
LJA: Lj1g3v4081860.1(Lj1g3v4081860.1)
LANG: 109326958
FVE: 101310387
PPER: 18789678 18789708 18789709 18792412
PMUM: 103319005 103319006 103319007 103344449
PAVI: 110765625 110765626 110765627 110765628 110771536
MDM: 103402429 103411054 103425389 103428961 103431803 103441965
PXB: 103944996 103944997 103944999 103946365 103946366
ZJU: 107431535
CSV: 101217257
CMO: 103486874
MCHA: 111019821 111019822
CMAX: 111482281
CMOS: 111441713
RCU: 8277408 8277879 8277880
JCU: 105636120
HBR: 110668477
JRE: 109008126 109008127 109016658 109019007
VVI: 100263633
SLY: 101246092 101247849 101261765 101262063 101262367
SPEN: 107001769 107001863 107002593 107008188 107028331
SOT: 102578406 102578747 102585799 102586130 102590105 102590484 102590830 102590870 102593896 102603170 102606401 107059425
CANN: 107839366 107844023 107844024
NTA: 107767804 107768690 107771987 107792896 107797681 107800961 107803600 107824233(CYP98A33v1)
NSY: 104216569 104221515 104228627 104235549
NTO: 104088297 104092594 104112912 104119156
INI: 109159148
SIND: 105162700 105172202
OEU: 111391169 111401521
HAN: 110865896 110895770
BVG: 104887604 104889547 104889649 104889748
SOE: 110778982 110779503 110799229
NNU: 104588272
OSA: 4339188
DOSA: Os05t0494000-01(Os05g0494000) Os10t0196100-00(Os10g0196100)
OBR: 102712257
BDI: 100835531
ATS: 109731922(LOC109731922) 109752053(LOC109752053) 109757203(LOC109757203) 109771147(LOC109771147) 109771148(LOC109771148) 109771149(LOC109771149) 109775586(LOC109775586)
SBI: 8077042 8082405
ZMA: 100191539 100274274 103649031
SITA: 101771055
PDA: 103705056 103706282
EGU: 105033349 105052441
MUS: 103995155
DCT: 110101632
AOF: 109819911
ATR: 18427105 18441256
SMO: SELMODRAFT_450942(C3'H1-1) SELMODRAFT_450943(C3'H1-2)
 » show all
Taxonomy
Reference
1  [PMID:2821918]
  Authors
Kuhnl T, Koch U, Heller W, Wellmann E.
  Title
Chlorogenic acid biosynthesis: characterization of a light-induced microsomal 5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase from carrot (Daucus carota L.) cell suspension cultures.
  Journal
Arch. Biochem. Biophys. 258 (1987) 226-32.
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.36
IUBMB Enzyme Nomenclature: 1.14.13.36
ExPASy - ENZYME nomenclature database: 1.14.13.36
BRENDA, the Enzyme Database: 1.14.13.36
CAS: 112131-08-5
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