KEGG   ENZYME: 1.14.13.36Help
Entry
EC 1.14.13.36               Enzyme                                 

Name
5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase;
5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase;
coumaroylquinate(coumaroylshikimate) 3'-monooxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
trans-5-O-(4-coumaroyl)-D-quinate,NADPH:oxygen oxidoreductase (3'-hydroxylating)
Reaction(IUBMB)
trans-5-O-(4-coumaroyl)-D-quinate + NADPH + H+ + O2 = trans-5-O-caffeoyl-D-quinate + NADP+ + H2O [RN:R04342]
Reaction(KEGG)
R04342;
(other) R06582
Show
Substrate
trans-5-O-(4-coumaroyl)-D-quinate [CPD:C12208];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
trans-5-O-caffeoyl-D-quinate [CPD:C00852];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Comment
Also acts on trans-5-O-(4-coumaroyl)shikimate.
History
EC 1.14.13.36 created 1990
Pathway
ec00940  Phenylpropanoid biosynthesis
ec00941  Flavonoid biosynthesis
ec00945  Stilbenoid, diarylheptanoid and gingerol biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K09754  coumaroylquinate(coumaroylshikimate) 3'-monooxygenase
Genes
RSS: 109440930
ATH: AT2G40890(CYP98A3)
ALY: ARALYDRAFT_903389
CSAT: 104782574 104785308 104792955
EUS: EUTSA_v10016538mg EUTSA_v10017706mg
BRP: 103857960 103865848 103866522
BNA: 106352767 106386334 106391625 106395719 106431114 106438010 106454525
BOE: 106335822 106340718 106342398
THJ: 104803227
CPAP: 110811301
CIT: 102624231
TCC: 18598608
DZI: 111293639
GMX: 100811080 606506(CYP98A2)
VRA: 106753926
VAR: 108346061
CCAJ: 109802555
CAM: 101502624
ADU: 107494128
AIP: 107604697
LJA: Lj1g3v4081860.1(Lj1g3v4081860.1)
LANG: 109326958
FVE: 101310387
ZJU: 107431535
CSV: 101217257
CMO: 103486874
CMAX: 111482281
CMOS: 111441713
JCU: 105636120
HBR: 110668477
VVI: 100263633
INI: 109159148
NNU: 104588272
OSA: 4339188
DOSA: Os05t0494000-01(Os05g0494000) Os10t0196100-00(Os10g0196100)
OBR: 102712257
BDI: 100835531
ATS: 109731922(LOC109731922) 109752053(LOC109752053) 109757203(LOC109757203) 109771147(LOC109771147) 109771148(LOC109771148) 109771149(LOC109771149) 109775586(LOC109775586)
SITA: 101771055
MUS: 103995155
DCT: 110101632
AOF: 109819911
SMO: SELMODRAFT_450942(C3'H1-1) SELMODRAFT_450943(C3'H1-2)
 » show all
Taxonomy
Reference
1  [PMID:2821918]
  Authors
Kuhnl T, Koch U, Heller W, Wellmann E.
  Title
Chlorogenic acid biosynthesis: characterization of a light-induced microsomal 5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase from carrot (Daucus carota L.) cell suspension cultures.
  Journal
Arch. Biochem. Biophys. 258 (1987) 226-32.
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.36
IUBMB Enzyme Nomenclature: 1.14.13.36
ExPASy - ENZYME nomenclature database: 1.14.13.36
BRENDA, the Enzyme Database: 1.14.13.36
CAS: 112131-08-5

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