KEGG   ENZYME: 1.14.13.44Help
Entry
EC 1.14.13.44               Enzyme                                 

Name
2-hydroxybiphenyl 3-monooxygenase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
2-hydroxybiphenyl,NADH:oxygen oxidoreductase (3-hydroxylating)
Reaction(IUBMB)
2-hydroxybiphenyl + NADH + H+ + O2 = 2,3-dihydroxybiphenyl + NAD+ + H2O [RN:R03964]
Reaction(KEGG)
Substrate
2-hydroxybiphenyl [CPD:C02499];
NADH [CPD:C00004];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
2,3-dihydroxybiphenyl [CPD:C02526];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Comment
Also converts 2,2'-dihydroxybiphenyl into 2,2',3-trihydroxy-biphenyl.
History
EC 1.14.13.44 created 1992
Reference
1  [PMID:3214154]
  Authors
Kohler HP, Kohler-Staub D, Focht DD.
  Title
Degradation of 2-hydroxybiphenyl and 2,2'-dihydroxybiphenyl by Pseudomonas sp. strain HBP1.
  Journal
Appl. Environ. Microbiol. 54 (1988) 2683-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
118251-39-1

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