Entry |
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Name |
dihydrochelirubine 12-monooxygenase;
dihydrochelirubine 12-hydroxylase
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Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
 |
Sysname |
dihydrochelirubine,NADPH:oxygen oxidoreductase (12-hydroxylating)
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Reaction(IUBMB) |
dihydrochelirubine + NADPH + H+ + O2 = 12-hydroxydihydrochelirubine + NADP+ + H2O [RN: R04708]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
A heme-thiolate protein (P-450)
|
History |
EC 1.14.13.57 created 1999
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Pathway |
ec00950 | Isoquinoline alkaloid biosynthesis |
ec01110 | Biosynthesis of secondary metabolites |
|
Reference |
1 |
Authors |
Kammerer, L., De-Eknamkul, W. and Zenk, M.H. |
Title |
Enzymic 12-hydroxylation and 12-O-methylation of dihydrochelirubine in dihydromacarpine formation by Thalictrum bulgaricum. |
Journal |
Phytochemistry 36 (1994) 1409-1416. |
Other DBs |
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