KEGG ENZYME: 1.14.19.39

ENZYME: 1.14.19.39

Entry

EC 1.14.19.39               Enzyme

Name

acyl-lipid Delta12-acetylenase

Class

Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water

Sysname

Delta12 acyl-lipid,ferrocytochrome-b5:oxygen oxidoreductase (12,13-dehydrogenating)

Reaction(IUBMB)

linoleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = crepenynyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O

Reaction(KEGG)

(other) R05740

Substrate

linoleoyl-[glycerolipid] [CPD:C21529];
ferrocytochrome b5 [CPD:C00999];
O2 [CPD:C00007];
H+ [CPD:C00080]

Product

crepenynyl-[glycerolipid];
ferricytochrome b5 [CPD:C00996];
H2O [CPD:C00001]

Comment

The enzyme, characterized from the plant Crepis alpina, converts the double bond at position 12 of linoleate into a triple bond. The product is the main fatty acid found in triacylglycerols in the seed oil of Crepis alpina.

History

EC 1.14.19.39 created 2000 as EC 1.14.99.33, transferred 2015 to EC 1.14.19.39

Pathway

ec00591

Linoleic acid metabolism

Orthology

K08262

acyl-lipid delta12-acetylenase

Reference

Authors

Banas, A., Bafor, M., Wiberg, E., Lenman, M., Staahl, U. and Stymne, S.

Title