| Entry |
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| Name |
plasmanylethanolamine desaturase;
alkylacylglycerophosphoethanolamine desaturase;
alkylacylglycero-phosphorylethanolamine dehydrogenase;
dehydrogenase, alkyl-acylglycerophosphorylethanolamine;
1-O-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine desaturase;
1-O-alkyl 2-acyl-sn-glycero-3-phosphorylethanolamine desaturase
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| Class |
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2;
Miscellaneous
 |
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| Sysname |
O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine,hydrogen-donor:oxygen oxidoreductase
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| Reaction(IUBMB) |
O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + A + 2 H2O [RN: R04571]
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| Reaction(KEGG) |
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| Substrate |
O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine [CPD: C04475];
AH2 [CPD: C00030];
O2 [CPD: C00007]
|
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| Product |
O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine [CPD: C04756];
A [CPD: C00028];
H2O [CPD: C00001]
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| Comment |
Requires NADPH or NADH. May involve cytochrome b5. Requires Mg2+ and ATP.
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| Pathway |
| Ether lipid metabolism | | Metabolic pathways |
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| Reference |
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| Authors |
Paltauf F, Holasek A. |
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| Title |
Enzymatic synthesis of plasmalogens. Characterization of the 1-O-alkyl-2-acyl-8n-glycero-3-phosphorylethanolamine desaturase from mucosa of hamster small intestine. |
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| Journal |
J. Biol. Chem. 248 (1973) 1609-15. |
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| Organism |
Mesocricetus auratus |
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| Reference |
|
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| Authors |
Wykle RL, Blank ML, Malone B, Snyder F. |
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| Title |
Evidence for a mixed function oxidase in the biosynthesis of ethanolamine plasmalogens from 1-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine. |
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| Journal |
J. Biol. Chem. 247 (1972) 5442-7. |
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| Organism |
Rattus norvegicus [GN: rno] |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 39391-13-4 |
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