| Entry |
|
|---|
| Name |
kynurenine 7,8-hydroxylase;
kynurenic acid hydroxylase;
kynurenic hydroxylase;
kynurenate 7,8-hydroxylase |
|---|
| Class |
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or
reduction of oxygen. The oxygen incorporated need not be derived
from O2;
Miscellaneous
 |
|---|
| Sysname |
kynurenate,hydrogen-donor:oxygen oxidoreductase (hydroxylating) |
|---|
| Reaction(IUBMB) |
kynurenate + AH2 + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + A
[RN:R03441] |
|---|
| Reaction(KEGG) |
R03441 > R03439 R03440
 |
|---|
| Substrate |
kynurenate [CPD:C01717];
AH2 [CPD:C00030];
O2 [CPD:C00007] |
|---|
| Product |
7,8-dihydro-7,8-dihydroxykynurenate [CPD:C01249];
A [CPD:C00028] |
|---|
| Pathway |
ec00380 Tryptophan metabolism |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:13984873]
TANIUCHI H, HAYAISHI O.
Studies on the metabolism of kynurenic acid. III. Enzymatic
formation of 7,8-dihydroxykynurenic acid from kynurenic acid.
J. Biol. Chem. 238 (1963) 283-93.
Pseudomonas fluorescens |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.14.99.2
IUBMB Enzyme Nomenclature: 1.14.99.2
ExPASy - ENZYME nomenclature database: 1.14.99.2
BRENDA, the Enzyme Database: 1.14.99.2
CAS: 9029-63-4 |
|---|
