KEGG   ENZYME: 1.14.99.20Help
Entry
EC 1.14.99.20               Enzyme                                 

Name
phylloquinone monooxygenase (2,3-epoxidizing);
phylloquinone epoxidase;
vitamin K 2,3-epoxidase;
vitamin K epoxidase;
vitamin K1 epoxidase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
Miscellaneous
BRITE hierarchy
Sysname
phylloquinone,hydrogen-donor:oxygen oxidoreductase (2,3-epoxidizing)
Reaction(IUBMB)
phylloquinone + AH2 + O2 = 2,3-epoxyphylloquinone + A + H2O [RN:R03510]
Reaction(KEGG)
Substrate
phylloquinone [CPD:C02059];
AH2 [CPD:C00030];
O2 [CPD:C00007]
Product
2,3-epoxyphylloquinone [CPD:C05849];
A [CPD:C00028];
H2O [CPD:C00001]
History
EC 1.14.99.20 created 1976
Reference
1  [PMID:4155625]
  Authors
Willingham AK, Matschiner JT.
  Title
Changes in phylloquinone epoxidase activity related to prothrombin synthesis and microsomal clotting activity in the rat.
  Journal
Biochem. J. 140 (1974) 435-41.
  Organism
Rattus norvegicus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
54596-37-1

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