KEGG   ENZYME: 1.14.99.21Help
Entry
EC 1.14.99.21               Enzyme                                 
Name
Latia-luciferin monooxygenase (demethylating);
luciferase (Latia luciferin);
Latia luciferin monooxygenase (demethylating)
Class
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2;
Miscellaneous
BRITE hierarchy
Sysname
Latia-luciferin,hydrogen-donor:oxygen oxidoreductase (demethylating)
Reaction(IUBMB)
Latia luciferin + AH2 + 2 O2 = oxidized Latia luciferin + CO2 + formate + A + H2O + hnu [RN:R03907]
Reaction(KEGG)
Substrate
Latia luciferin [CPD:C02293];
AH2 [CPD:C00030];
O2 [CPD:C00007]
Product
oxidized Latia luciferin [CPD:C03527];
CO2 [CPD:C00011];
formate [CPD:C00058];
A [CPD:C00028];
H2O [CPD:C00001];
hnu [CPD:C00205]
Comment
A flavoprotein. Latia is a bioluminescent mollusc. The reaction possibly involves two enzymes, an oxygenase followed by a monooxygenase for the actual light-emitting step.
Reference
1  [PMID:5650377]
  Authors
Shimomura O, Johnson FH.
  Title
The structure of Latia luciferin.
  Journal
Biochemistry. 7 (1968) 1734-8.
  Organism
Latia neritoides
Reference
2  [PMID:4506078]
  Authors
Shimomura O, Johnson FH, Kohama Y.
  Title
Reactions involved in bioluminescence systems of limpet (Latia neritoides) and luminous bacteria.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 69 (1972) 2086-9.
  Organism
Latia neritoides
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
62213-54-1
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