| Entry |
|
|---|
| Name |
steroid 9alpha-monooxygenase;
steroid 9alpha-hydroxylase |
|---|
| Class |
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or
reduction of oxygen. The oxygen incorporated need not be derived
from O2;
Miscellaneous
 |
|---|
| Sysname |
steroid,hydrogen-donor:oxygen oxidoreductase (9-epoxidizing) |
|---|
| Reaction(IUBMB) |
pregna-4,9(11)-diene-3,20-dione + AH2 + O2 =
9,11alpha-epoxypregn-4-ene-3,20-dione + A + H2O [RN:R04392] |
|---|
| Reaction(KEGG) |
R04392
 |
|---|
| Substrate |
pregna-4,9(11)-diene-3,20-dione [CPD:C04084];
AH2 [CPD:C00030];
O2 [CPD:C00007] |
|---|
| Product |
9,11alpha-epoxypregn-4-ene-3,20-dione [CPD:C04379];
A [CPD:C00028];
H2O [CPD:C00001] |
|---|
| Cofactor |
FMN [CPD:C00061];
Iron-sulfur [CPD:C00824] |
|---|
| Comment |
An enzyme system involving a flavoprotein (FMN) and two iron-sulfur
proteins. |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:7173200]
Strijewski A.
The steroid-9 alpha-hydroxylation system from Nocardia species.
Eur. J. Biochem. 128 (1982) 125-35.
Nocardia sp. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.14.99.24
IUBMB Enzyme Nomenclature: 1.14.99.24
ExPASy - ENZYME nomenclature database: 1.14.99.24
BRENDA, the Enzyme Database: 1.14.99.24
CAS: 82869-33-8 |
|---|
