| Entry |
|
|---|
| Name |
myristoyl-CoA 11-(E) desaturase |
|---|
| Class |
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or
reduction of oxygen. The oxygen incorporated need not be derived
from O2;
Miscellaneous
 |
|---|
| Sysname |
n-tetradecanoyl-CoA,NAD(P)H:O2 oxidoreductase [11-(E) desaturating] |
|---|
| Reaction(IUBMB) |
myristoyl-CoA + NAD(P)H + H+ + O2 = (E)-11-tetradecenoyl-CoA +
NAD(P)+ + 2 H2O [RN:R05321 R07216] |
|---|
| Reaction(KEGG) |
R05321 R07216
 |
|---|
| Substrate |
myristoyl-CoA [CPD:C02593];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007] |
|---|
| Product |
(E)-11-tetradecenoyl-CoA [CPD:C06736];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H2O [CPD:C00001] |
|---|
| Comment |
Involved in sex pheromone synthesis in the moth Spodoptera
littoralis. (E)-11-Tetradecenoyl-CoA is formed by stereospecific
removal of the pro-R H at C-11 and the pro-S H at C-12. EC
1.14.99.32, myristoyl-CoA 11-(Z) desaturase, forms the Z isomer by
stereospecific cleavage of pro-R H at C-11 and C-12. |
|---|
Reference
Authors
Title
Journal
|
1
Navaro, I., Font, I., Fabrias, G. and Camps, F.
Stereospecificity of the (E)- and (Z)-11 myristoyl desaturases in
the biosynthesis of Spodoptera littoralis sex pheromone.
J. Am. Chem. Soc. 119 (1997) 11335-11336. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.14.99.31
IUBMB Enzyme Nomenclature: 1.14.99.31
ExPASy - ENZYME nomenclature database: 1.14.99.31
BRENDA, the Enzyme Database: 1.14.99.31
CAS: 199543-17-4 |
|---|
