KEGG   ENZYME: 1.14.99.43Help
Entry
EC 1.14.99.43               Enzyme                                 

Name
beta-amyrin 24-hydroxylase;
sophoradiol 24-hydroxylase;
CYP93E1
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
Miscellaneous
BRITE hierarchy
Sysname
beta-amyrin,AH2:oxygen oxidoreductase (24-hydroxylating)
Reaction(IUBMB)
(1) beta-amyrin + AH2 + O2 = 24-hydroxy-beta-amyrin + A + H2O [RN:R09604];
(2) sophoradiol + AH2 + O2 = 24-hydroxysophoradiol + A + H2O [RN:R09605]
Reaction(KEGG)
Substrate
beta-amyrin [CPD:C08616];
AH2 [CPD:C00030];
O2 [CPD:C00007];
sophoradiol [CPD:C19733]
Product
24-hydroxy-beta-amyrin [CPD:C19732];
A [CPD:C00028];
H2O [CPD:C00001];
24-hydroxysophoradiol [CPD:C08980]
Comment
A heme-thiolate protein (P-450).
History
EC 1.14.99.43 created 2011
Pathway
Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K15814  
beta-amyrin 24-hydroxylase
Genes
GMX: 
100037459(CYP93E1)
CAM: 
Taxonomy
Reference
1  [PMID:16478469]
  Authors
Shibuya M, Hoshino M, Katsube Y, Hayashi H, Kushiro T, Ebizuka Y
  Title
Identification of beta-amyrin and sophoradiol 24-hydroxylase by expressed sequence tag mining and functional expression assay.
  Journal
FEBS. J. 273 (2006) 948-59.
  Sequence
[gmx:100037459]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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