KEGG   ENZYME: 1.14.99.45Help
Entry
EC 1.14.99.45               Enzyme                                 

Name
carotene epsilon-monooxygenase;
CYP97C1;
LUT1
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
Miscellaneous
BRITE hierarchy
Sysname
alpha-carotene:oxygen oxidoreductase (3-hydroxylating)
Reaction(IUBMB)
alpha-carotene + AH2 + O2 = alpha-cryptoxanthin + A + H2O [RN:R07850]
Reaction(KEGG)
R07850;
(other) R07531
Show
Substrate
alpha-carotene [CPD:C05433];
AH2 [CPD:C00030];
O2 [CPD:C00007]
Product
alpha-cryptoxanthin [CPD:C15981];
A [CPD:C00028];
H2O [CPD:C00001]
Comment
A heme-thiolate protein (P-450). Also acts on zeinoxanthin to give lutein.
History
EC 1.14.99.45 created 2011
Pathway
Carotenoid biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K09837  
carotene epsilon-monooxygenase
Genes
ATH: 
AT3G53130(LUT1)
ALY: 
CRB: 
EUS: 
BRP: 
CIT: 
CIC: 
TCC: 
EGR: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
POP: 
VVI: 
SLY: 
100322877(CYP97C11)
SOT: 
BVG: 
OSA: 
DOSA: 
Os10t0546600-01(Os10g0546600)
OBR: 
BDI: 
SBI: 
SORBI_01g030050(SORBIDRAFT_01g030050)
ZMA: 
SITA: 
PDA: 
MUS: 
SMO: 
PPP: 
VCN: 
OLU: 
OTA: 
BPG: 
MIS: 
MPP: 
CSL: 
CVR: 
 » show all
Taxonomy
Reference
1  [PMID:8837513]
  Authors
Pogson B, McDonald KA, Truong M, Britton G, DellaPenna D
  Title
Arabidopsis carotenoid mutants demonstrate that lutein is not essential for photosynthesis in higher plants.
  Journal
Plant. Cell. 8 (1996) 1627-39.
  Sequence
[ath:AT3G53130]
Reference
2  [PMID:14709673]
  Authors
Tian L, Musetti V, Kim J, Magallanes-Lundback M, DellaPenna D.
  Title
The Arabidopsis LUT1 locus encodes a member of the cytochrome p450 family that is required for carotenoid epsilon-ring hydroxylation activity.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 402-7.
  Sequence
[ath:AT3G53130]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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