KEGG   ENZYME: 1.14.99.45Help
Entry
EC 1.14.99.45               Enzyme                                 
Name
carotene epsilon-monooxygenase;
CYP97C1;
LUT1
Class
Oxidoreductases;
Acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2;
Miscellaneous
BRITE hierarchy
Sysname
alpha-carotene:oxygen oxidoreductase (3-hydroxylating)
Reaction(IUBMB)
alpha-carotene + AH2 + O2 = alpha-cryptoxanthin + A + H2O [RN:R07850]
Reaction(KEGG)
R07850;
(other) R07531
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Substrate
alpha-carotene [CPD:C05433];
AH2 [CPD:C00030];
O2 [CPD:C00007]
Product
alpha-cryptoxanthin [CPD:C15981];
A [CPD:C00028];
H2O [CPD:C00001]
Comment
A heme-thiolate protein (P450). Also acts on zeinoxanthin to give lutein.
Pathway
Carotenoid biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K09837  
carotene epsilon-monooxygenase
Genes
ATH: 
AT3G53130(LUT1)
ALY: 
GMX: 
MTR: 
CSV: 
RCU: 
POP: 
POPTR_589522(CYP97C4)
VVI: 
OSA: 
DOSA: 
Os10t0546600-01(Os10g0546600)
BDI: 
100835344
SBI: 
SORBI_01g030050(SORBIDRAFT_01g030050)
PPP: 
PHYPADRAFT_197852
VCN: 
VOLCADRAFT_83281
OLU: 
OSTLU_33533
OTA: 
Ot09g02560
 » show all
Taxonomy
Reference
1  [PMID:8837513]
  Authors
Pogson B, McDonald KA, Truong M, Britton G, DellaPenna D
  Title
Arabidopsis carotenoid mutants demonstrate that lutein is not essential for photosynthesis in higher plants.
  Journal
Plant. Cell. 8 (1996) 1627-39.
Reference
2  [PMID:14709673]
  Authors
Tian L, Musetti V, Kim J, Magallanes-Lundback M, DellaPenna D.
  Title
The Arabidopsis LUT1 locus encodes a member of the cytochrome p450 family that is required for carotenoid epsilon-ring hydroxylation activity.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 402-7.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
DBGET integrated database retrieval system