KEGG   ENZYME: 1.16.1.6Help
Entry
EC 1.16.1.6                 Enzyme                                 

Name
cyanocobalamin reductase (cyanide-eliminating);
cyanocobalamin reductase;
cyanocobalamin reductase (NADPH, cyanide-eliminating);
cyanocobalamin reductase (NADPH;
CN-eliminating);
NADPH:cyanocob(III)alamin oxidoreductase (cyanide-eliminating)
Class
Oxidoreductases;
Oxidizing metal ions;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
cob(I)alamin, cyanide:NADP+ oxidoreductase
Reaction(IUBMB)
cob(I)alamin + cyanide + NADP+ = cyanocob(III)alamin + NADPH + H+ [RN:R02999]
Reaction(KEGG)
Substrate
cob(I)alamin [CPD:C00853];
cyanide [CPD:C00177];
NADP+ [CPD:C00006]
Product
cyanocob(III)alamin [CPD:C02823];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
A flavoprotein.
History
EC 1.16.1.6 created 1989 as EC 1.6.99.12, transferred 2002 to EC 1.16.1.6
Pathway
Porphyrin and chlorophyll metabolism
Reference
1  [PMID:3134526]
  Authors
Watanabe F, Oki Y, Nakano Y, Kitaoka S.
  Title
Occurrence and characterization of cyanocobalamin reductase (NADPH; CN-eliminating) involved in decyanation of cyanocobalamin in Euglena gracilis.
  Journal
J. Nutr. Sci. Vitaminol. (Tokyo). 34 (1988) 1-10.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
131145-00-1

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