KEGG   ENZYME: 1.17.2.2Help
Entry
EC 1.17.2.2                 Enzyme                                 

Name
lupanine 17-hydroxylase (cytochrome c);
lupanine dehydrogenase (cytochrome c)
Class
Oxidoreductases;
Acting on CH or CH2 groups;
With a cytochrome as acceptor
BRITE hierarchy
Sysname
lupanine:cytochrome c-oxidoreductase (17-hydroxylating)
Reaction(IUBMB)
lupanine + 2 ferricytochrome c + H2O = 17-hydroxylupanine + 2 ferrocytochrome c + 2 H+ [RN:R09938]
Reaction(KEGG)
Substrate
lupanine [CPD:C10772];
ferricytochrome c [CPD:C00125];
H2O [CPD:C00001]
Product
17-hydroxylupanine [CPD:C20233];
ferrocytochrome c [CPD:C00126];
H+ [CPD:C00080]
Comment
The enzyme isolated from Pseudomonas putida contains heme c and requires pyrroloquinoline quinone (PQQ) for activity
History
EC 1.17.2.2 created 2012
Reference
1  [PMID:1656935]
  Authors
Hopper DJ, Rogozinski J, Toczko M
  Title
Lupanine hydroxylase, a quinocytochrome c from an alkaloid-degrading Pseudomonas  sp.
  Journal
Biochem. J. 279 ( Pt 1) (1991) 105-9.
  Sequence
Reference
2  [PMID:12686118]
  Authors
Hopper DJ, Kaderbhai MA
  Title
The quinohaemoprotein lupanine hydroxylase from Pseudomonas putida.
  Journal
Biochim. Biophys. Acta. 1647 (2003) 110-5.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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