KEGG   ENZYME: 1.18.1.7Help
Entry
EC 1.18.1.7                 Enzyme                                 

Name
ferredoxin---NAD(P)+ reductase (naphthalene dioxygenase ferredoxin-specific);
NADH-ferredoxin(NAP) reductase
Class
Oxidoreductases;
Acting on iron-sulfur proteins as donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
ferredoxin:NAD(P)+ oxidoreductase
Reaction(IUBMB)
2 reduced [2Fe-2S] ferredoxin + NAD(P)+ + H+ = 2 oxidized [2Fe-2S] ferredoxin + NAD(P)H
Substrate
reduced [2Fe-2S] ferredoxin;
NAD+ [CPD:C00003];
NADP+ [CPD:C00006];
H+ [CPD:C00080]
Product
oxidized [2Fe-2S] ferredoxin;
NADH [CPD:C00004];
NADPH [CPD:C00005]
Comment
The enzyme from the aerobic bacterium Ralstonia sp. U2 donates electrons to both EC 1.14.12.12, naphthalene 1,2-dioxygenase and EC 1.14.13.172, salicylate 5-hydroxylase [1]. The enzyme from Pseudomonas NCIB 9816 is specific for the ferredoxin associated with naphthalene dioxygenase; it contains FAD and a [2Fe-2S] cluster.
History
EC 1.18.1.7 created 2013
Orthology
K14581  
naphthalene 1,2-dioxygenase ferredoxin reductase component
Genes
EBT: 
PSC: 
PSTU: 
PBM: 
ALT: 
MMW: 
MME: 
MPC: 
RSO: 
RSc1091(nagAa)
RSL: 
RSN: 
RSM: 
RSE: 
RPJ: 
RMN: 
CBW: 
BMK: 
DM80_1434(ndoR) DM80_1439(ndoR)
BUG: 
BUQ: 
BPX: 
BFN: 
OI25_3043(ndoR)
PPK: 
PPNO: 
PPNM: 
PRB: 
PPUL: 
PSPU: 
PAPI: 
PVE: 
POX: 
PFG: 
PNR: 
AXY: 
POL: 
PNA: 
AAV: 
AJS: 
AAA: 
ACK: 
VPE: 
LCH: 
THI: 
AZO: 
azo2517(nagAa)
SIX: 
OAH: 
RBM: 
SGI: 
TMO: 
TMO_2240(ndoR)
 » show all
Taxonomy
Reference
1  [PMID:11872705]
  Authors
Zhou NY, Al-Dulayymi J, Baird MS, Williams PA.
  Title
Salicylate 5-hydroxylase from Ralstonia sp. strain U2: a monooxygenase with close relationships to and shared electron transport proteins with naphthalene dioxygenase.
  Journal
J. Bacteriol. 184 (2002) 1547-55.
  Sequence
Reference
2  [PMID:2294092]
  Authors
Haigler BE, Gibson DT
  Title
Purification and properties of NADH-ferredoxinNAP reductase, a component of naphthalene dioxygenase from Pseudomonas sp. strain NCIB 9816.
  Journal
J. Bacteriol. 172 (1990) 457-64.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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