KEGG   ENZYME: 1.2.1.29Help
Entry
EC 1.2.1.29                 Enzyme                                 

Name
aryl-aldehyde dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
aryl-aldehyde:NAD+ oxidoreductase
Reaction(IUBMB)
an aromatic aldehyde + NAD+ + H2O = an aromatic acid + NADH + H+ [RN:R01486]
Reaction(KEGG)
Substrate
aromatic aldehyde [CPD:C00193];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
aromatic acid [CPD:C00539];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Oxidizes a number of aromatic aldehydes, but not aliphatic aldehydes.
History
EC 1.2.1.29 created 1972
Pathway
Tyrosine metabolism
Xylene degradation
Metabolic pathways
Microbial metabolism in diverse environments
Reference
1  [PMID:4289834]
  Authors
Raison JK, Henson G, Rienits KG.
  Title
The oxidation of gentisaldehyde by nicotinamide-adenine dinucleotide-specific, aromatic aldehyde dehydrogenase from rabbit liver.
  Journal
Biochim. Biophys. Acta. 118 (1966) 285-98.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
37250-94-5

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