KEGG   ENZYME: 1.2.1.30Help
Entry
EC 1.2.1.30                 Enzyme                                 

Name
aryl-aldehyde dehydrogenase (NADP+);
aromatic acid reductase;
aryl-aldehyde dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
aryl-aldehyde:NADP+ oxidoreductase (ATP-forming)
Reaction(IUBMB)
an aromatic aldehyde + NADP+ + AMP + diphosphate + H2O = an aromatic acid + NADPH + H+ + ATP [RN:R01490]
Reaction(KEGG)
Substrate
aromatic aldehyde [CPD:C00193];
NADP+ [CPD:C00006];
AMP [CPD:C00020];
diphosphate [CPD:C00013];
H2O [CPD:C00001]
Product
aromatic acid [CPD:C00539];
NADPH [CPD:C00005];
H+ [CPD:C00080];
ATP [CPD:C00002]
History
EC 1.2.1.30 created 1972
Reference
1  [PMID:4405494]
  Authors
Gross GG.
  Title
Formation and reduction of intermediate acyladenylate by aryl-aldehyde. NADP oxidoreductase from Neurospora crassa.
  Journal
Eur. J. Biochem. 31 (1972) 585-92.
  Organism
Neurospora crassa
Reference
2  [PMID:4389863]
  Authors
Gross GG, Zenk MH.
  Title
[Reduction of aromatic acids to aldehydes and alcohols in the cell-free system. 1. Purification and properties of aryl-aldehyde: NADP-oxidoreductase from Neurospora crassa]
  Journal
Eur. J. Biochem. 8 (1969) 413-9.
  Organism
Neurospora crassa
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9074-94-6

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