KEGG   ENZYME: 1.2.1.4Help
Entry
EC 1.2.1.4                  Enzyme                                 

Name
aldehyde dehydrogenase (NADP+);
NADP-acetaldehyde dehydrogenase;
NADP-dependent aldehyde dehydrogenase;
aldehyde dehydrogenase (NADP)
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
aldehyde:NADP+ oxidoreductase
Reaction(IUBMB)
an aldehyde + NADP+ + H2O = a carboxylate + NADPH + H+ [RN:R00634]
Reaction(KEGG)
Substrate
aldehyde [CPD:C00071];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Product
carboxylate [CPD:C00060];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.2.1.4 created 1961
Pathway
Caprolactam degradation
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K14519  
NADP-dependent aldehyde dehydrogenase
Genes
POL: 
AAV: 
AAA: 
PDE: 
HBA: 
RHA: 
ROP: 
SCO: 
SCO1871(SCI39.18c)
SMA: 
SGR: 
SCB: 
CMI: 
CMS: 
ART: 
AAU: 
AAur_3317(aldH)
ACH: 
RSA: 
BCV: 
MPH: 
NCA: 
KFL: 
TFU: 
NDA: 
SRO: 
FRE: 
GOB: 
SEN: 
AMD: 
PDX: 
AMI: 
CAI: 
SNA: 
TBI: 
CWO: 
RBA: 
FTE: 
 » show all
Taxonomy
Reference
1
  Authors
Adachi, O., Matsushita, K., Shinagawa, E. and Ameyama, M.
  Title
Crystallization and properties of NADP-dependent aldehyde dehydrogenase from Gluconobacter melanogenus.
  Journal
Agric. Biol. Chem. 44 (1980) 155-164.
Reference
2
  Authors
Jakoby, W.B.
  Title
Aldehyde dehydrogenases.
  Journal
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 203-221.
Reference
3
  Authors
Nakayama, T.
  Title
Acetic acid bacteria. II. Intracellular distribution of enzymes related to acetic acid fermentation, and some properties of a highly purified triphosphopyridine nucleotide (TPN)-dependent aldehyde dehydrogenase.
  Journal
J. Biochem. (Tokyo) 48 (1960) 812-830.
Reference
4  [PMID:13061400]
  Authors
SEEGMILLER JE.
  Title
Triphosphopyridine nucleotide-linked aldehyde dehydrogenase from yeast.
  Journal
J. Biol. Chem. 201 (1953) 629-37.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9028-87-9

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