KEGG   ENZYME: 1.2.1.42Help
Entry
EC 1.2.1.42                 Enzyme                                 

Name
hexadecanal dehydrogenase (acylating);
fatty acyl-CoA reductase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
hexadecanal:NAD+ oxidoreductase (CoA-acylating)
Reaction(IUBMB)
hexadecanal + CoA + NAD+ = hexadecanoyl-CoA + NADH + H+ [RN:R01277]
Reaction(KEGG)
Substrate
hexadecanal [CPD:C00517];
CoA [CPD:C00010];
NAD+ [CPD:C00003]
Product
hexadecanoyl-CoA [CPD:C00154];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Also acts, more slowly, on octadecanoyl-CoA.
History
EC 1.2.1.42 created 1978
Reference
1  [PMID:4343165]
  Authors
Johnson RC, Gilbertson JR.
  Title
Isolation, characterization, and partial purification of a fatty acyl coenzyme A reductase from bovine cardiac muscle.
  Journal
J. Biol. Chem. 247 (1972) 6991-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
72561-01-4

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