KEGG   ENZYME: 1.2.1.43Help
Entry
EC 1.2.1.43                 Enzyme                                 

Name
formate dehydrogenase (NADP+);
NADP+-dependent formate dehydrogenase;
formate dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
formate:NADP+ oxidoreductase
Reaction(IUBMB)
formate + NADP+ = CO2 + NADPH [RN:R00134]
Reaction(KEGG)
Substrate
formate [CPD:C00058];
NADP+ [CPD:C00006]
Product
CO2 [CPD:C00011];
NADPH [CPD:C00005]
Comment
A tungsten-selenium-iron protein.
History
EC 1.2.1.43 created 1978
Pathway
Methane metabolism
Carbon fixation pathways in prokaryotes
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K05299  
formate dehydrogenase alpha subunit
K15022  
formate dehydrogenase beta subunit
Genes
LHK: 
WSU: 
WS0477(FDHB)
TDN: 
SUA: 
SKU: 
SULR: 
NSA: 
NIS: 
SUN: 
SLH: 
GSU: 
GSU0509(sfrA) GSU0510(sfrB)
GSK: 
GME: 
Gmet_3022(sfrA) Gmet_3023(sfrB)
GUR: 
GLO: 
GBM: 
Gbem_0659(sfrB) Gbem_0660(sfrA)
GEO: 
Geob_1607(sfrB) Geob_1608(sfrA)
GEM: 
GEB: 
GPI: 
GSB: 
PCA: 
Pcar_2503(sfrB)
DES: 
DEU: 
DVU: 
DVL: 
DVG: 
DDS: 
DBA: 
DAL: 
DAT: 
HRM2_16890(fdhA6) HRM2_26590(gltD1)
DTO: 
DAO: 
DTI: 
DBR: 
RPA: 
RPE: 
RPT: 
RPX: 
BVR: 
DSY: 
DSY3968(fdhF)
DHD: 
DDH: 
DDL: 
DAE: 
DCA: 
DGI: 
DAU: 
TJR: 
SGY: 
DOR: 
DAI: 
DMI: 
DED: 
DEC: 
DRS: 
HMO: 
HM1_1745(fdhA)
CAD: 
CHY: 
CHY_0733(fdhA)
MTA: 
ADG: 
TOC: 
NTH: 
AAR: 
DDF: 
DAP: 
CNI: 
FSI: 
 » show all
Taxonomy
Reference
1  [PMID:4154039]
  Authors
Andreesen JR, Ljungdahl LG.
  Title
Nicotinamide adenine dinucleotide phosphate-dependent formate dehydrogenase from Clostridium thermoaceticum: purification and properties.
  Journal
J. Bacteriol. 120 (1974) 6-14.
Reference
2  [PMID:6822536]
  Authors
Yamamoto I, Saiki T, Liu SM, Ljungdahl LG.
  Title
Purification and properties of NADP-dependent formate dehydrogenase from Clostridium thermoaceticum, a tungsten-selenium-iron protein.
  Journal
J. Biol. Chem. 258 (1983) 1826-32.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
51377-43-6

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