KEGG   ENZYME: 1.2.1.54Help
Entry
EC 1.2.1.54                 Enzyme                                 

Name
gamma-guanidinobutyraldehyde dehydrogenase;
alpha-guanidinobutyraldehyde dehydrogenase;
4-guanidinobutyraldehyde dehydrogenase;
GBAL dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
4-guanidinobutanal:NAD+ 1-oxidoreductase
Reaction(IUBMB)
4-guanidinobutanal + NAD+ + H2O = 4-guanidinobutanoate + NADH + 2 H+ [RN:R03177]
Reaction(KEGG)
Substrate
4-guanidinobutanal [CPD:C02647];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
4-guanidinobutanoate [CPD:C01035];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the degradation of arginine in Pseudomonas putida (cf. EC 1.2.1.19 aminobutyraldehyde dehydrogenase).
History
EC 1.2.1.54 created 1989
Pathway
Arginine and proline metabolism
Metabolic pathways
Orthology
K12254  
4-guanidinobutyraldehyde dehydrogenase / NAD-dependent aldehyde dehydrogenase
Genes
SLQ: 
PAE: 
PAEV: 
PAEI: 
PAU: 
PAP: 
PAG: 
PAF: 
PNC: 
PAEB: 
PDK: 
PSG: 
PRP: 
PAEP: 
PAER: 
PAEM: 
PAEL: 
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PAEU: 
PAEG: 
PAEC: 
PAEO: 
PMY: 
PMK: 
PRE: 
PPSE: 
PPU: 
PPF: 
PPG: 
PPW: 
PPT: 
PPB: 
PPI: 
PPX: 
PPUH: 
PPUT: 
PPUN: 
PPUD: 
PFV: 
PMON: 
PMOT: 
PMOS: 
PPJ: 
POR: 
PST: 
PSB: 
PSYR: 
PSP: 
PCI: 
PFL: 
PPRC: 
PPRO: 
PFO: 
PFS: 
PFLU_5976(aldH)
PFE: 
PFC: 
PFN: 
PFW: 
PFB: 
PFF: 
PPZ: 
PMAN: 
PTV: 
PEN: 
PSEEN5424(aldH)
PSA: 
PSZ: 
PSR: 
PSC: 
PSJ: 
PSH: 
PSTU: 
PSTT: 
PBM: 
PBA: 
PBC: 
PPUU: 
PDR: 
PSV: 
PSK: 
PKC: 
PKB_5073(puuc3) PKB_5650(puuc5)
PCH: 
PCZ: 
PCP: 
PFZ: 
PALK: 
PRH: 
PSW: 
PPV: 
PSES: 
PSEM: 
PSEC: 
PPSY: 
PSOS: 
AVN: 
AVL: 
AVD: 
ACX: 
LAL: 
SAGA: 
BLEP: 
MME: 
GSN: 
AHY: 
AHD: 
AHR: 
AHP: 
AHJ: 
AHH: 
AHI: 
AVR: 
AMED: 
ASR: 
OCE: 
BMK: 
JAG: 
MASW: 
MEH: 
HAT: 
RPM: 
TXI: 
SVL: 
SRC: 
 » show all
Taxonomy
Reference
1
  Authors
Yorifuji, T., Koike, K., Sakurai, T. and Yokoyama, K.
  Title
4-Aminobutyraldehyde and 4-guanidinobutyraldehyde dehydrogenases for arginine degradation in Pseudomonas putida.
  Journal
Agric. Biol. Chem. 50 (1986) 2009-2016.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
56831-75-5

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