KEGG   ENZYME: 1.2.1.61Help
Entry
EC 1.2.1.61                 Enzyme                                 

Name
4-hydroxymuconic-semialdehyde dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
4-hydroxymuconic-semialdehyde:NAD+ oxidoreductase
Reaction(IUBMB)
4-hydroxymuconic semialdehyde + NAD+ + H2O = maleylacetate + NADH + 2 H+ [RN:R05236]
Reaction(KEGG)
Substrate
4-hydroxymuconic semialdehyde [CPD:C06603];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
maleylacetate [CPD:C02222];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the 4-nitrophenol degradation pathway.
History
EC 1.2.1.61 created 2000
Pathway
Chlorocyclohexane and chlorobenzene degradation
Microbial metabolism in diverse environments
Reference
1  [PMID:16348446]
  Authors
Spain JC, Gibson DT.
  Title
Pathway for Biodegradation of p-Nitrophenol in a Moraxella sp.
  Journal
Appl. Environ. Microbiol. 57 (1991) 812-819.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 

DBGET integrated database retrieval system