KEGG   ENZYME: 1.2.1.65Help
Entry
EC 1.2.1.65                 Enzyme                                 

Name
salicylaldehyde dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
salicylaldehyde:NAD+ oxidoreductase
Reaction(IUBMB)
salicylaldehyde + NAD+ + H2O = salicylate + NADH + 2 H+ [RN:R02941]
Reaction(KEGG)
Substrate
salicylaldehyde [CPD:C06202];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
salicylate [CPD:C00805];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the naphthalene degradation pathway in some bacteria.
History
EC 1.2.1.65 created 2000, modified 2011
Pathway
Naphthalene degradation
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K00152  
salicylaldehyde dehydrogenase
Genes
PSC: 
PSTU: 
PBM: 
RMN: 
BMK: 
PNA: 
Taxonomy
Reference
1  [PMID:1447127]
  Authors
Eaton RW, Chapman PJ.
  Title
Bacterial metabolism of naphthalene: construction and use of recombinant bacteria to study ring cleavage of 1,2-dihydroxynaphthalene and subsequent reactions.
  Journal
J. Bacteriol. 174 (1992) 7542-54.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
55354-34-2

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