KEGG   ENZYME: 1.2.1.77Help
Entry
EC 1.2.1.77                 Enzyme                                 

Name
3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+);
BoxD;
3,4-dehydroadipyl-CoA semialdehyde dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
3,4-didehydroadipyl-CoA semialdehyde:NADP+ oxidoreductase
Reaction(IUBMB)
3,4-didehydroadipyl-CoA semialdehyde + NADP+ + H2O = 3,4-didehydroadipyl-CoA + NADPH + H+ [RN:R09554]
Reaction(KEGG)
Substrate
3,4-didehydroadipyl-CoA semialdehyde [CPD:C19683];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Product
3,4-didehydroadipyl-CoA [CPD:C19682];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
This enzyme catalyses a step in the aerobic benzoyl-coenzyme A catabolic pathway in Azoarcus evansii and Burkholderia xenovorans.
History
EC 1.2.1.77 created 2010
Orthology
K15514  
3,4-dehydroadipyl-CoA semialdehyde dehydrogenase
Genes
REH: 
H16_B1917(h16_B1917)
CNC: 
CTI: 
BUG: 
BGF: 
BUQ: 
BXE: 
BXB: 
DR64_3583(paaN)
BPX: 
BPY: 
BFN: 
OI25_2712(paaN)
BPT: 
Bpet3573(paaZ2)
RFR: 
POL: 
PNA: 
ACK: 
VAP: 
VPE: 
VPD: 
CTT: 
LCH: 
THI: 
EBA: 
ebA2759(boxZ)
AZO: 
AZA: 
AZKH_4516(boxZ)
AZI: 
MAG: 
 » show all
Taxonomy
Reference
1  [PMID:16585753]
  Authors
Gescher J, Ismail W, Olgeschlager E, Eisenreich W, Worth J, Fuchs G
  Title
Aerobic benzoyl-coenzyme A (CoA) catabolic pathway in Azoarcus evansii: conversion of ring cleavage product by 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase.
  Journal
J. Bacteriol. 188 (2006) 2919-27.
  Sequence
Reference
2  [PMID:18462753]
  Authors
Bains J, Boulanger MJ
  Title
Structural and biochemical characterization of a novel aldehyde dehydrogenase encoded by the benzoate oxidation pathway in Burkholderia xenovorans LB400.
  Journal
J. Mol. Biol. 379 (2008) 597-608.
  Sequence
[bxe:Bxe_A1420]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 

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