KEGG   ENZYME: 1.2.1.82Help
Entry
EC 1.2.1.82                 Enzyme                                 

Name
beta-apo-4'-carotenal oxygenase;
beta-apo-4'-carotenal dehydrogenase;
YLO-1;
carD (gene name)
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
4'-apo-beta,psi-carotenal:NAD+ oxidoreductase
Reaction(IUBMB)
4'-apo-beta,psi-caroten-4'-al + NAD+ + H2O = neurosporaxanthin + NADH + 2 H+ [RN:R09783]
Reaction(KEGG)
Substrate
4'-apo-beta,psi-caroten-4'-al [CPD:C19892];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
neurosporaxanthin [CPD:C08607];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Neurosporaxanthin is responsible for the orange color of of Neurospora.
History
EC 1.2.1.82 created 2011
Pathway
Carotenoid biosynthesis
Metabolic pathways
Orthology
K17819  
beta-apo-4'-carotenal oxygenase
Genes
NCR: 
NCU04013(ylo-1)
NTE: 
NEUTE1DRAFT140784(NEUTE1DRAFT_140784)
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
FPU: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
VDA: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_364184(AO090009000222)
ANG: 
ANI_1_1254014(An01g09260)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
PBN: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
FME: 
 » show all
Taxonomy
Reference
1  [PMID:18627463]
  Authors
Estrada AF, Youssar L, Scherzinger D, Al-Babili S, Avalos J
  Title
The ylo-1 gene encodes an aldehyde dehydrogenase responsible for the last reaction in the Neurospora carotenoid pathway.
  Journal
Mol. Microbiol. 69 (2008) 1207-20.
  Sequence
[ncr:NCU04013]
Reference
2  [PMID:21749649]
  Authors
Diaz-Sanchez V, Estrada AF, Trautmann D, Al-Babili S, Avalos J
  Title
The gene carD encodes the aldehyde dehydrogenase responsible for neurosporaxanthin biosynthesis in Fusarium fujikuroi.
  Journal
FEBS. J. 278 (2011) 3164-76.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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