| Entry |
|
|---|
| Name |
carbon-monoxide dehydrogenase (cytochrome b-561);
carbon monoxide oxidase;
carbon monoxide oxygenase (cytochrome b-561);
carbon monoxide:methylene blue oxidoreductase;
CO dehydrogenase;
carbon-monoxide dehydrogenase |
|---|
| Class |
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With a cytochrome as acceptor
 |
|---|
| Sysname |
carbon monoxide,water:cytochrome b-561 oxidoreductase |
|---|
| Reaction(IUBMB) |
CO + H2O + 2 ferricytochrome b-561 = CO2 + 2 H+ + 2 ferrocytochrome
b-561 [RN:R04698] |
|---|
| Reaction(KEGG) |
R04698;
(other) R00276
 |
|---|
| Substrate |
CO [CPD:C00237];
H2O [CPD:C00001];
ferricytochrome b-561 [CPD:C05305] |
|---|
| Product |
CO2 [CPD:C00011];
H+ [CPD:C00080];
ferrocytochrome b-561 [CPD:C05183] |
|---|
| Comment |
Contains molybdopterin cytosine dinucleotide, FAD and
[2Fe-2S]-clusters. Oxygen, methylene blue and iodonitrotetrazolium
chloride can act as nonphysiological electron acceptors. |
|---|
| Orthology |
KO: K05891 carbon-monoxide dehydrogenase (cytochrome b-561) |
|---|
| Genes |
DME: Dmel_CG8776
 |
|---|
Reference
Authors
Title
Journal
|
1
Meyer, O., Jacobitz, S. and Kruger, B.
Biochemistry and physiology of aerobic carbon monoxide-utilizing
bacteria.
FEMS Microbiol. Rev. 39 (1986) 161-179. |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:2808305]
Jacobitz S, Meyer O.
Removal of CO dehydrogenase from Pseudomonas carboxydovorans
cytoplasmic membranes, rebinding of CO dehydrogenase to depleted
membranes, and restoration of respiratory activities.
J. Bacteriol. 171 (1989) 6294-9.
Pseudomonas carboxydovorans |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:7354006]
Meyer O, Schlegel HG.
Carbon monoxide:methylene blue oxidoreductase from Pseudomonas
carboxydovorans.
J. Bacteriol. 141 (1980) 74-80.
Pseudomonas carboxydovorans |
|---|
Reference
Authors
Title
Journal
Organism
|
4 [PMID:10430865]
Dobbek H, Gremer L, Meyer O, Huber R.
Crystal structure and mechanism of CO dehydrogenase, a molybdo
iron-sulfur flavoprotein containing S-selanylcysteine.
Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 8884-9.
Oligotropha carboxidovorans |
|---|
Reference
Authors
Title
Journal
Organism
|
5 [PMID:10966817]
Hanzelmann P, Dobbek H, Gremer L, Huber R, Meyer O.
The effect of intracellular molybdenum in Hydrogenophaga pseudoflava
on the crystallographic structure of the seleno-molybdo-iron-sulfur
flavoenzyme carbon monoxide dehydrogenase.
J. Mol. Biol. 301 (2000) 1221-35.
Hydrogenophaga pseudoflava |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.2.2.4
IUBMB Enzyme Nomenclature: 1.2.2.4
ExPASy - ENZYME nomenclature database: 1.2.2.4
UM-BBD (Biocatalysis/Biodegradation Database): 1.2.2.4
BRENDA, the Enzyme Database: 1.2.2.4
CAS: 395639-79-9 |
|---|
