KEGG   ENZYME: 1.20.2.1Help
Entry
EC 1.20.2.1                 Enzyme                                 

Name
arsenate reductase (cytochrome c);
arsenite oxidase (ambiguous)
Class
Oxidoreductases;
Acting on phosphorus or arsenic in donors;
With a cytochrome as acceptor
BRITE hierarchy
Sysname
arsenite:cytochrome c oxidoreductase
Reaction(IUBMB)
arsenite + H2O + 2 oxidized cytochrome c = arsenate + 2 reduced cytochrome c + 2 H+ [RN:R09787]
Reaction(KEGG)
Substrate
arsenite [CPD:C06697];
H2O [CPD:C00001];
oxidized cytochrome c
Product
arsenate [CPD:C11215];
reduced cytochrome c [CPD:C00126];
H+ [CPD:C00080]
Comment
A molybdoprotein containing iron-sulfur clusters. Isolated from alpha-proteobacteria. Unlike EC 1.20.9.1, arsenate reductase (azurin), it does not use azurin as acceptor.
History
EC 1.20.2.1 created 2011
Orthology
K08355  
arsenite oxidase small subunit
K08356  
arsenite oxidase large subunit
Genes
VSP: 
MBS: 
MPQ: 
MVS: 
MVIS_1833(aoxA)
RSL: 
CBW: 
BOC: 
BVE: 
BMU: 
BMJ: 
BMK: 
PPNO: 
AXX: 
RFR: 
HAR: 
HEAR0478(aoxB) HEAR0479(aoxA)
TIN: 
THI: 
THI_3162(aoxB) THI_3163(aoxA)
SBA: 
SMUL: 
SMUL_3119(aioB) SMUL_3120(aioA)
SHAL: 
AAK: 
NHA: 
XAU: 
SNO: 
CHEL: 
MSC: 
CSE: 
RLI: 
PSF: 
CON: 
HAT: 
DAA: 
AMV: 
PGV: 
VIR: 
PMS: 
PMQ: 
PMW: 
CAU: 
CAG: 
CHL: 
TTJ: 
TTS: 
TSC: 
TAQ: 
CPB: 
CLI: 
HHO: 
HYS: 
TRD: 
NDE: 
NIDE3704(aoxA) NIDE3705(aoxB)
APE: 
ACJ: 
STO: 
SULA: 
MCN: 
AHO: 
PYR: 
POG: 
 » show all
Taxonomy
Reference
1  [PMID:15178476]
  Authors
vanden Hoven RN, Santini JM
  Title
Arsenite oxidation by the heterotroph Hydrogenophaga sp. str. NT-14: the arsenite oxidase and its physiological electron acceptor.
  Journal
Biochim. Biophys. Acta. 1656 (2004) 148-55.
Reference
2  [PMID:17306216]
  Authors
Santini JM, Kappler U, Ward SA, Honeychurch MJ, vanden Hoven RN, Bernhardt PV
  Title
The NT-26 cytochrome c552 and its role in arsenite oxidation.
  Journal
Biochim. Biophys. Acta. 1767 (2007) 189-96.
Reference
3  [PMID:19525272]
  Authors
Branco R, Francisco R, Chung AP, Morais PV
  Title
Identification of an aox system that requires cytochrome c in the highly arsenic-resistant bacterium Ochrobactrum tritici SCII24.
  Journal
Appl. Environ. Microbiol. 75 (2009) 5141-7.
  Sequence
Reference
4  [PMID:20421652]
  Authors
Lieutaud A, van Lis R, Duval S, Capowiez L, Muller D, Lebrun R, Lignon S, Fardeau ML, Lett MC, Nitschke W, Schoepp-Cothenet B
  Title
Arsenite oxidase from Ralstonia sp. 22: characterization of the enzyme and its interaction with soluble cytochromes.
  Journal
J. Biol. Chem. 285 (2010) 20433-41.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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