| Entry |
|
|---|
| Name |
arsenate reductase (glutaredoxin) |
|---|
| Class |
Oxidoreductases;
Acting on phosphorus or arsenic in donors;
With disulfide as acceptor
 |
|---|
| Sysname |
glutharedoxin:arsenate oxidoreductase |
|---|
| Reaction(IUBMB) |
arsenate + glutaredoxin = arsenite + glutaredoxin disulfide + H2O
[RN:R05747] |
|---|
| Reaction(KEGG) |
R05747
 |
|---|
| Substrate |
arsenate [CPD:C11215];
glutaredoxin [CPD:C07292] |
|---|
| Product |
arsenite [CPD:C06697];
glutaredoxin disulfide [CPD:C07293];
H2O [CPD:C00001] |
|---|
| Comment |
A molybdoenzyme. The glutaredoxins catalyse glutathione-disulfide
oxidoreductions and have a redox-active disulfide/dithiol in the
active site (-Cys-Pro-Tyr-Cys-) that forms a disulfide bond in the
oxidized form [2, 10]. Glutaredoxins have a binding site for
glutathione, which is required to reduce them to the dithiol form
[3, 6]. Thioredoxins reduced by NADPH and thioredoxin reductase can
act as alternative substrates. The enzyme [1, 4, 7, 9] is part of a
system for detoxifying arsenate. Although the arsenite formed is
more toxic than arsenate, it can be extruded from some bacteria by
EC 3.6.3.16, arsenite-transporting ATPase; in other organisms,
arsenite can be methylated by EC 2.1.1.137, arsenite
methyltransferase, in a pathway to non-toxic organoarsenical
compounds. |
|---|
| Orthology |
KO: K00537 arsenate reductase
KO: K03741 arsenate reductase |
|---|
| Genes |
AFM: AFUA_1G16090 AFUA_5G15000
ECO: b2495(yfgD) b3503(arsC)
ECJ: JW2480(yfgD) JW3470(arsC)
ECD: ECDH10B_2661(yfgD) ECDH10B_3679(arsC)
EBW: BWG_2259(yfgD) BWG_3193(arsC)
ECE: Z3758 Z4905(arsC)
ECS: ECs3357 ECs4375
ECF: ECH74115_3717(arsC1) ECH74115_4852(arsC2)
ETW: ECSP_3434(yfgD)
ECG: E2348C_2720(yfgD) E2348C_3739(arsC)
ECC: c3012 c4301(arsC)
ECI: UTI89_C2811(yfgD) UTI89_C4021(arsC)
ECP: ECP_2497 ECP_3592
ECV: APECO1_2952(arsC) APECO1_4074(yfgD)
ECW: EcE24377A_3986(arsC)
ECX: EcHS_A2629(arsC1) EcHS_A3705(arsC2)
ECM: EcSMS35_2642(arsC1) EcSMS35_3795(arsC)
ECY: ECSE_2781 ECSE_3769
ECL: EcolC_0213 EcolC_1181
ECK: EC55989_2780(yfgD) EC55989_3944(arsC)
ECQ: ECED1_2918(yfgD) ECED1_4172(arsC)
ECR: ECIAI1_2547(yfgD) ECIAI1_3650(arsC)
ECT: ECIAI39_2636(yfgD) ECIAI39_3995(arsC)
ECZ: ECS88_2666(yfgD) ECS88_3908(arsC)
EUM: ECUMN_2808(yfgD) ECUMN_3993(arsC)
ELF: LF82_0152(arsC) LF82_3093(yfgD)
EBL: B21_02349(yfgD) B21_03305(arsC)
EBD: ECBD_0237 ECBD_1193
EBR: ECB_02387(yfgD) ECB_03352(arsC)
EFE: EFER_0681(yfgD) EFER_3499(arsC)
STY: STY2736
STT: t0362
SPT: SPA0372(yfgD)
SEK: SSPA0348
SPQ: SPAB_00451 SPAB_05419
SEI: SPC_1162(yfgD)
SEC: SC2492(yfgD)
SEH: SeHA_C2754(arsC) SeHA_C3264
SEE: SNSL254_A2690(arsC)
SEW: SeSA_A0718(arsC) SeSA_A2732(arsC)
SEA: SeAg_B2642(arsC)
SED: SeD_A2863(arsC)
SEG: SG2527(yfgD)
SET: SEN2476(yfgD)
SES: SARI_00385 SARI_01919
STM: STM2495(yfgD)
YPE: YPO3070(yfgD)
YPK: y1411
YPM: YP_2692(arsC2)
YPA: YPA_2261
YPN: YPN_1314
YPG: YpAngola_A3126(arsC)
YPP: YPDSF_2174
YPS: YPTB2791(yfgD)
YPI: YpsIP31758_1238(arsC)
YPY: YPK_1355
YPB: YPTS_2896
YEN: YE1131(yfgD) YE3364(arsC) YE3475(arsC2)
SFL: SF2539 SF3536(arsC)
SFX: S2688 S4234(arsC)
SFV: SFV_2540 SFV_3515(arsC)
SSN: SSON_2577 SSON_3738(arsC)
SBO: SBO_2516 SBO_3501(arsC)
SBC: SbBS512_E2869(arsC1) SbBS512_E3818(arsC2)
SDY: SDY_2684 SDY_3559(arsC)
ECA: ECA1258 ECA1603(arsC)
PCT: PC1_1133
ETA: ETA_10610(arsC)
PLU: plu2751
PAY: PAU_01790
SGL: SG0250 SG2069
ENT: Ent638_2979 Ent638_4257
ESA: ESA_00766 ESA_pESA3p05485
CTU: Ctu_30780(yfgD)
KPN: KPN_02817(yfgD) KPN_03303(arsC) KPN_pKPN3p05922(arsC)
KPE: KPK_0801(arsC_1) KPK_1318 KPK_A0056(arsC_2)
KPU: KP1_4069(yfgD) KP1_4590(arsC)
CKO: CKO_00301
SPE: Spro_2389 Spro_3518
PMR: PMI1569
EIC: NT01EI_1195
DDA: Dd703_1068 Dd703_3114
DZE: Dd1591_2988
HIN: HI0236
HIT: NTHI0343(arsC)
HIP: CGSHiEE_01895
HIQ: CGSHiGG_03815
HDU: HD0631(arsC)
HSO: HS_1002(arsC)
HSM: HSM_1480
PMU: PM1130 PM1944
MSU: MS1959(arsC)
APL: APL_1089(arsC)
APJ: APJL_1105(arsC)
APA: APP7_1147
AAP: NT05HA_2151
AAT: D11S_0091
XCC: XCC0686(arsC)
XCB: XC_3548
XCA: xccb100_3671
XCV: XCV3637(arsC)
XAC: XAC3512(arsC)
XOO: XOO1073(arsC)
XOM: XOO_0974
XOP: PXO_00627 PXO_02434
SML: Smlt2421(arsC)
VCH: VC2165
VCO: VC0395_A1745(arsC)
VCM: VCM66_2088(arsC)
VCJ: VCD_002210
VVU: VV1_1906
VVY: VV2509
VPA: VP2279
VHA: VIBHAR_03194
VSP: VS_2312
VFI: VF_1923(yfgD)
VFM: VFMJ11_2058(arsC)
VSA: VSAL_I2385
PPR: PBPRA0845 PBPRA2903
PAE: PA0950 PA2279(arsC)
PAU: PA14_35100(arsC) PA14_51980
PAP: PSPA7_2962(arsC2) PSPA7_4559(arsC1)
PAG: PLES_43651
PPU: PP_1645(arsC-1) PP_2716(arsC-3)
PPF: Pput_3036 Pput_4072 Pput_4193
PPG: PputGB1_1140 PputGB1_1247
PPW: PputW619_1207 PputW619_4088
PST: PSPTO_1529 PSPTO_1687(arsC)
PSB: Psyr_1337 Psyr_3702
PSP: PSPPH_3723(arsC)
PFL: PFL_1171 PFL_2184(arsC) PFL_4456(arsC)
PFO: Pfl01_2398 Pfl01_4228
PFS: PFLU3782
PEN: PSEEN1354 PSEEN3308(arsC)
PMY: Pmen_2989 Pmen_3058
PSA: PST_0236 PST_0240(arsC-3) PST_2824(arsC-1) PST_2838
CJA: CJA_2283(arsC)
AVN: Avin_36820
PAR: Psyc_0953
PCR: Pcryo_1465
PRW: PsycPRwf_0674 PsycPRwf_1140
ACB: A1S_1452
ABY: ABAYE2200 ABAYE3656(arsC) ABAYE3658(arsC)
SON: SO_2871
SDN: Sden_1646
SFR: Sfri_1754
SAZ: Sama_1914
SBL: Sbal_1789 Sbal_2366
SBM: Shew185_1782 Shew185_2353
SBN: Sbal195_1826 Sbal195_2469
SBP: Sbal223_2496
SLO: Shew_1840 Shew_1863
SPC: Sputcn32_1214 Sputcn32_1694 Sputcn32_2122 Sputcn32_3830
SSE: Ssed_2438
SPL: Spea_1970
SHE: Shewmr4_2348
SHM: Shewmr7_2420
SHN: Shewana3_1648 Shewana3_2345
SHW: Sputw3181_2331 Sputw3181_2950
SHL: Shal_2329
SWD: Swoo_2168
SWP: swp_2745
ILO: IL1465
CPS: CPS_3178 CPS_3191(arsC)
PHA: PSHAa1133
PAT: Patl_2484
SDE: Sde_0900
MAQ: Maqu_0914 Maqu_2552
AMC: MADE_02143
PIN: Ping_1073
TTU: TERTU_3007(arsC)
LPN: lpg0248
LPF: lpl0302
LPP: lpp0318
LPC: LPC_0325
MCA: MCA1552 MCA2520(arsC)
FTU: FTT_0824(arsC1) FTT_1527c(arsC2)
FTF: FTF0824(arsC1) FTF1527c(arsC2)
FTW: FTW_0404 FTW_1362
FTL: FTL_0316 FTL_0587
FTH: FTH_0316(arsC1) FTH_0587(arsC2)
FTA: FTA_0335 FTA_0621
FTN: FTN_0339 FTN_1435
FPH: Fphi_0484 Fphi_1240 Fphi_1746
TCX: Tcr_1207
NOC: Noc_0186
AEH: Mlg_0826 Mlg_2712
HHA: Hhal_0091
TGR: Tgr7_2246
HCH: HCH_01858(arsC)
CSA: Csal_1896
ABO: ABO_1139 ABO_1544(arsC) ABO_2679(arsC-3)
MMW: Mmwyl1_2339
AHA: AHA_1678(arsC-1) AHA_1727(arsC-2)
ASA: ASA_0573(arsC) ASA_2681(arsC)
AFE: Lferr_2481
AFR: AFE_2860(arsC)
RMA: Rmag_0324
VOK: COSY_0305(arsC) COSY_0666
NMA: NMA0252
NME: NMB0005(arsC)
NMC: NMC2143
NMN: NMCC_0005(arsC)
NGO: NGO1924
CVI: CV_0770 CV_2439(arsC)
RSO: RSc3271 RSp1128(arsC)
RPI: Rpic_3469
RPF: Rpic12D_3141
REU: Reut_A1525 Reut_A1894 Reut_A3271
REH: H16_A2068(arsC1) H16_A2177 H16_A3585(arsC2)
RME: Rmet_0329 Rmet_3436
BMA: BMAA0558(arsC) BMAA2113
BMV: BMASAVP1_1142
BML: BMA10229_0913(arsC) BMA10229_1421
BMN: BMA10247_A1882(arsC) BMA10247_A2408
BPS: BPSS1432 BPSS2348
BPM: BURPS1710b_2595 BURPS1710b_A0456(arsC) BURPS1710b_A1502(arsC)
BPL: BURPS1106A_2506 BURPS1106A_A1942(arsC) BURPS1106A_A3174(arsC)
BPD: BURPS668_2450 BURPS668_A2037(arsC) BURPS668_A3287(arsC)
BTE: BTH_I2015 BTH_II0959 BTH_II2370(arsC)
BVI: Bcep1808_1937 Bcep1808_3796 Bcep1808_4683
BUR: Bcep18194_B0006 Bcep18194_C6562 Bcep18194_C6564
BCN: Bcen_5167
BCH: Bcen2424_5692
BCM: Bcenmc03_4544
BCJ: BCAM0002
BAM: Bamb_4964
BAC: BamMC406_3103
BMU: Bmul_2315 Bmul_3163 Bmul_6164 Bmul_6300
BMJ: BMULJ_00926(arsC1) BMULJ_05359(arsC1) BMULJ_06262(arsC1)
BXE: Bxe_A1669 Bxe_B0302 Bxe_B3030
BPE: BP1306(arsC)
BPA: BPP2716(arsC) BPP2912(arsC)
BBR: BB2782(arsC) BB2882(arsC)
BPT: Bpet1022(arsC1) Bpet2482(arsC2) Bpet4550(arsC3)
RFR: Rfer_3666
POL: Bpro_2219
PNA: Pnap_2586
AAV: Aave_0915
AJS: Ajs_1283 Ajs_3564
DAC: Daci_0491 Daci_1593
MPT: Mpe_A1583(arsC1) Mpe_A2343(arsC2)
HAR: HEAR0500(arsC) HEAR0502(arsC) HEAR1322 HEAR1960(arsCb)
HEAR1963(arsCa) HEAR3183 HEAR3207(arsC) HEAR3302(arsC)
MMS: mma_2071(arsC1) mma_3429(arsC2)
NEU: NE1678(yfgD)
NET: Neut_0441
NMU: Nmul_A1157
EBA: ebA5585
AZO: azo1658 azo2067 azo2351(arsC1) azo2353(arsC2)
DAR: Daro_2747
TBD: Tbd_1425
APP: CAP2UW1_4244
WSU: WS0753(arsC) WS0760
TDN: Suden_0149 Suden_0314
CJR: CJE1732(arsC)
CJU: C8J_1458(arsC)
ABU: Abu_1384 Abu_1935(arsC)
SUN: SUN_1381 SUN_1478
GSU: GSU2953(arsC)
GME: Gmet_0521
PCA: Pcar_1772
PPD: Ppro_0842
DVU: DVU1646(arsC)
DVL: Dvul_1440
DDE: Dde_2792 Dde_2793 Dde_2820
BBA: Bd0325
DPS: DP1879
DOL: Dole_2881
AFW: Anae109_3642
MXA: MXAN_3126 MXAN_5496
SCL: sce0191(arsC1) sce5614(arsC2) sce6040
SFU: Sfum_3601
MLO: mll2167
MES: Meso_0324 Meso_4201
PLA: Plav_0438
SME: SMc02649(arsC)
SMD: Smed_5055
ATU: Atu1490(arsC)
ATC: AGR_C_2748
RET: RHE_CH02532(ypch00851) RHE_CH02534(arsC)
RLE: RL2884(arsC1) RL2887(arsC2)
BME: BMEI0992
BMF: BAB1_0399 BAB1_1008
BMB: BruAb1_0995
BMC: BAbS19_I09350
BMS: BR0989
BMT: BSUIS_A1033(arsC)
BOV: BOV_0957(arsC)
BCS: BCAN_A1006(arsC)
OAN: Oant_0478 Oant_2198 Oant_3199
BJA: bll3084(arsC)
BRA: BRADO3724 BRADO4444(arsC) BRADO5106
BBT: BBta_3754 BBta_4662(arsC) BBta_5577
RPA: RPA2257(arsC1) RPA3554(arsC2) RPA3555(arsC3)
RPB: RPB_1971
RPC: RPC_0617
RPD: RPD_3418
RPE: RPE_3658 RPE_3659
RPT: Rpal_4072
NWI: Nwi_1913 Nwi_2033 Nwi_3124 Nwi_3125
NHA: Nham_2244 Nham_4429
OCA: OCAR_4231(arsC)
XAU: Xaut_0876 Xaut_3573
AZC: AZC_1271 AZC_3011 AZC_4550
MEX: Mext_1910 Mext_3865
MDI: p2METDI0028(arsC)
MRD: Mrad2831_1379
MET: M446_0521
MCH: Mchl_1048
BID: Bind_3399
CCR: CC_1503
CAK: Caul_1785 Caul_2487
SIL: SPO1276 SPO2908(arsC-1)
SIT: TM1040_2798
RSP: RSP_3127(arsC)
RSH: Rsph17029_3857
JAN: Jann_2102 Jann_2964
RDE: RD1_1071(arsC) RD1_1877 RD1_2397(arsC)
PDE: Pden_0215 Pden_2271 Pden_3135
DSH: Dshi_0846(arsC)
MMR: Mmar10_2255 Mmar10_2883
HNE: HNE_0991(arsC) HNE_3335 HNE_3533
NAR: Saro_3279
SAL: Sala_1826 Sala_2404 Sala_2539
SWI: Swit_2243 Swit_4697
ELI: ELI_00390
GBE: GbCGDNIH1_0188
ACR: Acry_2812
GDI: GDI_3649(arsC)
RRU: Rru_A1450 Rru_A1992
MAG: amb1831
MGM: Mmc1_0286
BSU: BSU24770(mgsR) BSU25780(arsC)
BHA: BH2861(spxA) BH2998(arsC) BH3485
BAN: BA3196(arsC) BA3456(spxA) BA5229
BAR: GBAA3196(arsC) GBAA3456(spxA) GBAA5229
BAA: BA_0099 BA_3707 BA_3951
BAT: BAS2971 BAS3202(spxA) BAS4860
BAH: BAMEG_1416(arsC) BAMEG_5285
BAI: BAA_3245(arsC) BAA_5264
BCE: BC3152 BC3402(spxA) BC4992
BCA: BCE_3207 BCE_3423(spxA) BCE_5131 BCE_A0158(arsC)
BCZ: BCZK2898(arsC) BCZK3109(spxA) BCZK4717(arsC)
BCR: BCAH187_A3434 BCAH187_A5134
BCB: BCB4264_A5136
BCU: BCAH820_5098 BCAH820_B0304(arsC2)
BCG: BCG9842_B0104
BCQ: BCQ_4809(arsC)
BCX: BCA_5127
BCY: Bcer98_3587
BTK: BT9727_2963(arsC) BT9727_3181(spxA) BT9727_4701(arsC)
BTL: BALH_2854(arsC) BALH_3060 BALH_4524(arsC)
BWE: BcerKBAB4_4815
BLI: BL01574 BL01871(arsC)
BLD: BLi02122(arsC) BLi02651(yqgZ)
BCL: ABC0837(arsC) ABC2528(spxA)
BAY: RBAM_023100(yqgZ)
BPU: BPUM_1077(spxA) BPUM_2207(yqgZ) BPUM_2939(arsC)
OIH: OB1213(spxA) OB2389 OB2423
GKA: GK0589 GK0817(spxA) GK3222
GTN: GTNG_0697(spxA) GTNG_1600 GTNG_2957
SAU: SA0856(spxA) SAP018(arsC)
SAV: SAV0997(spxA)
SAW: SAHV_0992(spxA)
SAM: MW0879(spxA)
SAR: SAR0692(arsC) SAR0965(spxA)
SAS: SAS0867(spxA)
SAC: SACOL1002(spxA) SACOL1824(arsC)
SAB: SAB0864(spxA) SAB1632
SAA: SAUSA300_0898(spxA) SAUSA300_1719(arsC)
SAX: USA300HOU_0839(arsC1) USA300HOU_0955(spxA)
USA300HOU_1764(arsC2)
SAO: SAOUHSC_00934(spxA) SAOUHSC_01894
SAJ: SaurJH9_0996(spxA)
SAH: SaurJH1_1015(spxA)
SAE: NWMN_0867(spxA) NWMN_1666(arsC)
SEP: SE0134 SE0686(spxA)
SER: SERP0209(arsC-1) SERP0576(spxA) SERP2431(arsC-2)
SHA: SH0101(arsC) SH0108(arsC) SH1961(spxA)
SSP: SSP1633 SSP1788(spxA) SSPP114
LMO: lmo2191(spxA)
LMF: LMOf2365_2224(spxA) LMOf2365_2397
LIN: lin2295(spxA)
LWE: lwe2208(spxA) lwe2373
LSP: Bsph_0536 Bsph_1216 Bsph_2626 Bsph_2988
ESI: Exig_0879 Exig_2050 Exig_2350
EAT: EAT1b_0545 EAT1b_0813
BBE: BBR47_33340(arsC)
LLA: L11493(arsC) L132585(yfdC)
LLC: LACR_0545 LACR_1707
LLM: llmg_0514 llmg_0902(arsC) llmg_1703
SPY: SPy_0891(arsC) SPy_1249(spxA)
SPZ: M5005_Spy_0697(arsC) M5005_Spy_0959(spxA)
SPM: spyM18_0952(arsC) spyM18_1198(spxA)
SPG: SpyM3_0610(arsC) SpyM3_0885(spxA)
SPS: SPs1085(spxA) SPs1243
SPH: MGAS10270_Spy0755(arsC) MGAS10270_Spy1074(spxA)
SPI: MGAS10750_Spy0789(arsC) MGAS10750_Spy1110(spxA)
SPJ: MGAS2096_Spy0769(arsC) MGAS2096_Spy1019(spxA)
SPK: MGAS9429_Spy0753(arsC) MGAS9429_Spy1063(spxA)
SPF: SpyM50839(spxA) SpyM51111 SpyM51521
SPA: M6_Spy0714 M6_Spy0949(spxA)
SPB: M28_Spy0677(arsC) M28_Spy0932(spxA)
SPN: SP_1405(spxA)
SPD: SPD_1236(spxA) SPD_1291
SPR: spr1262(spxA)
SPW: SPCG_1393(spxA)
SPX: SPG_1346(spxA)
SNE: SPN23F_13700(spxA)
SPV: SPH_1536(spxA) SPH_1578
SNM: SP70585_1444
SJJ: SPJ_1304
SNT: SPT_0869
SAG: SAG0996(spxA) SAG1181(arsC)
SAN: gbs1031(spxA) gbs1254
SAK: SAK_1091(spxA) SAK_1268(arsC) SAK_1582
SMU: SMU.1142c(spxA)
STC: str0997(spxA)
STL: stu0997(spxA)
STE: STER_0078 STER_1002
SSA: SSA_0937(spxA) SSA_1712
SSU: SSU05_1111(spxA) SSU05_1447
SSV: SSU98_1121(spxA) SSU98_1455
SGO: SGO_1051(spxA) SGO_1534
LPL: lp_0059(arsC) lp_2228(nrpR3)
LJO: LJ0232 LJ0818
LAC: LBA0641(arsC)
LSA: LSA1449(spxA)
LSL: LSL_0608(arsC) LSL_0888(arsC) LSL_1330(arsC)
LDB: Ldb0578(spx) Ldb1432
LBU: LBUL_0514
LBR: LVIS_0887 LVIS_1148 LVIS_2140
LCA: LSEI_1735 LSEI_2761
LGA: LGAS_1359
LRE: Lreu_0567
LHE: lhv_0688
PPE: PEPE_1207
EFA: EF2678
LME: LEUM_1704 LEUM_A11
LCI: LCK_00079(wzb) LCK_00420(spxA)
CAC: CA_P0105(arsC)
CPE: CPE0838 CPE2362
CPF: CPF_0834(arsC) CPF_2672
CPR: CPR_0827(arsC) CPR_2357
CTC: CTC01181
CBO: CBO0751(arsC) CBO1065
CBA: CLB_0793 CLB_1106
CBH: CLC_0808 CLC_1118
CBY: CLM_0908
CBL: CLK_0165(arsC) CLK_0511
CBB: CLD_3493 CLD_3802(arsC)
CBF: CLI_0832 CLI_1157
CBE: Cbei_2111 Cbei_2174
CKL: CKL_2533(arsC)
CKR: CKR_2244
CPY: Cphy_2155
CCE: Ccel_1068
AMT: Amet_0983
AOE: Clos_0632
STH: STH627
DSY: DSY4147 DSY4597 DSY4671
EEL: EUBELI_20104
TTE: TTE1001(wzb)
TEX: Teth514_1414
TPD: Teth39_0973
CSC: Csac_0638
ACL: ACL_1180(arsC)
MTU: Rv2643(arsC)
MTC: MT2720
MRA: MRA_2672(arsC)
MTF: TBFG_12661
MBO: Mb2676(arsC)
MBB: BCG_2670(arsC)
MLE: ML0247(arsC)
MLB: MLBr_00247(arsC)
MPA: MAP0982c(arsC)
MAV: MAV_1155(arsC)
MSM: MSMEG_5428(arsC)
MUL: MUL_4639
MVA: Mvan_4784
MGI: Mflv_1942
MAB: MAB_0992
MMC: Mmcs_4250
MKM: Mkms_4336
MJL: Mjls_4629
CGL: NCgl1049(cgl1094)
CGB: cg1244
CGT: cgR_1177
CEF: CE1150
CDI: DIP0965(arsC)
CJK: jk2004(arsC)
CUR: cur_0032
NFA: nfa24500 nfa24510 nfa31790
RHA: RHA1_ro03369 RHA1_ro05655
SCO: SCO2206(arsC) SCO6835(arsC)
SMA: SAV_5999(arsC)
SGR: SGR_5308
AAU: AAur_3630(arsC) AAur_pTC20058(arsC) AAur_pTC20061(arsC)
AAur_pTC20062(arsC)
NCA: Noca_3081
TFU: Tfu_1521
FAL: FRAAL3366
SEN: SACE_5142 SACE_5143 SACE_6023(arsC)
BLJ: BLD_0704(arsC1)
RXY: Rxyl_2878
PCU: pc1344(arsC)
LIL: LA3699(arsC)
LIC: LIC10527(arsC)
LBI: LEPBI_I2872(arsC) LEPBI_I3368
ABA: Acid345_2957
SUS: Acid_4408
BTH: BT_0115
BFS: BF3387
BVU: BVU_4187
SRU: SRU_2458
CHU: CHU_1588(arsC)
GFO: GFO_1803(arsC) GFO_3441
FJO: Fjoh_0740 Fjoh_4784
FPS: FP0352 FP1599 FP1603
COC: Coch_1881
OTE: Oter_3671
AMU: Amuc_0237
RBA: RB11147(arsC) RB11157(arsC)
SYN: slr0946(arsC)
SYW: SYNW1767
SYG: sync_2016
SYX: SynWH7803_0626
CYB: CYB_2366(arsC)
MAR: MAE_02540(arsC)
CYT: cce_2998(arsC)
GVI: glr0004
AVA: Ava_3712
PMA: Pro0511(arsC)
PMM: PMM0512
PMN: PMN2A_1845
PMB: A9601_05691(arsC)
PMC: P9515_05761(arsC)
PMF: P9303_07481(arsC)
PMG: P9301_05391(arsC)
PMH: P9215_05941(arsC)
PMJ: P9211_05131
PME: NATL1_05701(arsC)
AMR: AM1_0594(arsC)
CTE: CT1725(arsC)
CCH: Cag_0397
CPH: Cpha266_0465 Cpha266_0918
PVI: Cvib_1136 Cvib_1487
PLT: Plut_1703
DET: DET0143(arsC)
DEH: cbdb_A168(arsC)
DEB: DehaBAV1_0227
DRA: DR_A0123
DGE: Dgeo_2548 Dgeo_2770
TTH: TTC1502
TTJ: TTHA1853
AAE: aq_685(arsC)
PMO: Pmob_1954
DTH: DICTH_0400
MAC: MA3103(arsC)
MHU: Mhun_0874
MBN: Mboo_0218
MTH: MTH1355
AFU: AF1361(arsC)
HWA: HQ3170A(arsC) HQ3636A(arsC)
NPH: NP6092A(arsC)
PFU: PF0553
TKO: TK0843
 |
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| Structures |
PDB: 1RXE 1RXI 1S3C 1S3D 1SD8 1SD9 1SJZ 1SK0 1SK1 1SK2
1Z2D 1Z2E 3C1R 3C1S 3CTF 3CTG |
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Reference
Authors
Title
Journal
Organism
|
1 [PMID:8969183]
Gladysheva T, Liu J, Rosen BP.
His-8 lowers the pKa of the essential Cys-12 residue of the ArsC
arsenate reductase of plasmid R773.
J. Biol. Chem. 271 (1996) 33256-60.
Escherichia coli [GN:eco] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:8003492]
Gladysheva TB, Oden KL, Rosen BP.
Properties of the arsenate reductase of plasmid R773.
Biochemistry. 33 (1994) 7288-93.
Escherichia coli [GN:eco] |
|---|
Reference
Authors
Title
Journal
|
3 [PMID:7476363]
Holmgren A, Aslund F.
Glutaredoxin.
Methods. Enzymol. 252 (1995) 283-92. |
|---|
Reference
Authors
Title
Journal
|
4
Ji, G.Y., Garber, E.A.E., Armes, L.G., Chen, C.M., Fuchs, J.A. and
Silver, S.
Arsenate reductase of Staphylococcus aureus plasmid PI258.
Biochemistry 33 (1994) 7294-7299. |
|---|
Reference
Authors
Title
Journal
Organism
|
5 [PMID:9738904]
Krafft T, Macy JM.
Purification and characterization of the respiratory arsenate
reductase of Chrysiogenes arsenatis.
Eur. J. Biochem. 255 (1998) 647-53.
Chrysiogenes arsenatis |
|---|
Reference
Authors
Title
Journal
Organism
|
6 [PMID:7788290]
Martin JL.
Thioredoxin--a fold for all reasons.
Structure. 3 (1995) 245-50.
Escherichia coli [GN:eco] |
|---|
Reference
Authors
Title
Journal
Organism
|
7 [PMID:10606519]
Messens J, Hayburn G, Desmyter A, Laus G, Wyns L.
The essential catalytic redox couple in arsenate reductase from
Staphylococcus aureus.
Biochemistry. 38 (1999) 16857-65.
Staphylococcus aureus |
|---|
Reference
Authors
Title
Journal
Organism
|
8 [PMID:10649963]
Radabaugh TR, Aposhian HV.
Enzymatic reduction of arsenic compounds in mammalian systems:
reduction of arsenate to arsenite by human liver arsenate reductase.
Chem. Res. Toxicol. 13 (2000) 26-30.
Homo sapiens [GN:hsa] |
|---|
Reference
Authors
Title
Journal
Organism
|
9 [PMID:9537360]
Sato T, Kobayashi Y.
The ars operon in the skin element of Bacillus subtilis confers
resistance to arsenate and arsenite.
J. Bacteriol. 180 (1998) 1655-61.
Bacillus subtilis [GN:bsu] |
|---|
Reference
Authors
Title
Journal
Organism
|
10 [PMID:10593884]
Shi J, Vlamis-Gardikas A, Aslund F, Holmgren A, Rosen BP.
Reactivity of glutaredoxins 1, 2, and 3 from Escherichia coli shows
that glutaredoxin 2 is the primary hydrogen donor to ArsC-catalyzed
arsenate reduction.
J. Biol. Chem. 274 (1999) 36039-42.
Escherichia coli [GN:eco] |
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| Other DBs |
ExplorEnz - The Enzyme Database: 1.20.4.1
IUBMB Enzyme Nomenclature: 1.20.4.1
ExPASy - ENZYME nomenclature database: 1.20.4.1
UM-BBD (Biocatalysis/Biodegradation Database): 1.20.4.1
BRENDA, the Enzyme Database: 1.20.4.1
CAS: 146907-46-2 |
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