KEGG   ENZYME: 1.20.9.1Help
Entry
EC 1.20.9.1                 Enzyme                                 

Name
arsenate reductase (azurin);
arsenite oxidase (ambiguous)
Class
Oxidoreductases;
Acting on phosphorus or arsenic in donors;
With a copper protein as acceptor
BRITE hierarchy
Sysname
arsenite:azurin oxidoreductase
Reaction(IUBMB)
arsenite + H2O + 2 oxidized azurin = arsenate + 2 reduced azurin + 2 H+ [RN:R05751]
Reaction(KEGG)
R05751;
(other) R09787
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Substrate
arsenite [CPD:C06697];
H2O [CPD:C00001];
oxidized azurin [CPD:C05357]
Product
arsenate [CPD:C11215];
reduced azurin [CPD:C05358];
H+ [CPD:C00080]
Comment
Contains a molybdopterin centre comprising two molybdopterin guanosine dinucleotide cofactors bound to molybdenum, a [3Fe-4S] cluster and a Rieske-type [2Fe-2S] cluster. Isolated from beta-proteobacteria. Also uses a c-type cytochrome or O2 as acceptors.
History
EC 1.20.9.1 created 2001 as EC 1.20.98.1, transferred 2011 to EC 1.20.9.1
Orthology
K08355  
arsenite oxidase small subunit
K08356  
arsenite oxidase large subunit
Genes
VSP: 
MBS: 
MPQ: 
MVS: 
MVIS_1833(aoxA)
RSL: 
CBW: 
BOC: 
BVE: 
BMU: 
BMJ: 
BMK: 
PPNO: 
RFR: 
HAR: 
HEAR0478(aoxB) HEAR0479(aoxA)
TIN: 
THI: 
THI_3162(aoxB) THI_3163(aoxA)
SBA: 
SMUL: 
SMUL_3119(aioB) SMUL_3120(aioA)
AAK: 
NHA: 
XAU: 
SNO: 
CHEL: 
MSC: 
CSE: 
RLI: 
PSF: 
CON: 
HAT: 
DAA: 
AMV: 
PGV: 
VIR: 
PMS: 
PMQ: 
PMW: 
CAU: 
CAG: 
CHL: 
TTJ: 
TTS: 
TSC: 
TAQ: 
CPB: 
CLI: 
HHO: 
HYS: 
TRD: 
NDE: 
NIDE3704(aoxA) NIDE3705(aoxB)
APE: 
ACJ: 
STO: 
MCN: 
AHO: 
PYR: 
POG: 
 » show all
Taxonomy
Reference
1  [PMID:1331097]
  Authors
Anderson GL, Williams J, Hille R.
  Title
The purification and characterization of arsenite oxidase from Alcaligenes faecalis, a molybdenum-containing hydroxylase.
  Journal
J. Biol. Chem. 267 (1992) 23674-82.
  Sequence
Reference
2  [PMID:11250197]
  Authors
Ellis PJ, Conrads T, Hille R, Kuhn P.
  Title
Crystal structure of the 100 kDa arsenite oxidase from Alcaligenes faecalis in two crystal forms at 1.64 A and 2.03 A.
  Journal
Structure. (Camb). 9 (2001) 125-32.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
146907-46-2

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