| Entry |
|
|---|
| Name |
arsenate reductase (azurin);
arsenite oxidase |
|---|
| Class |
Oxidoreductases;
Acting on phosphorus or arsenic in donors;
With other, known, acceptors
 |
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| Sysname |
arsenite:azurin oxidoreductase |
|---|
| Reaction(IUBMB) |
arsenite + H2O + 2 azurinox = arsenate + 2 azurinred + 2 H+
[RN:R05751] |
|---|
| Reaction(KEGG) |
R05751
 |
|---|
| Substrate |
arsenite [CPD:C06697];
H2O [CPD:C00001];
azurinox [CPD:C05357] |
|---|
| Product |
arsenate [CPD:C11215];
azurinred [CPD:C05358];
H+ [CPD:C00080] |
|---|
| Comment |
Contains a molybdopterin centre comprising two molybdopterin
guanosine dinucleotide cofactors bound to molybdenum, a [3Fe-4S]
cluster and a Rieske-type [2Fe-2S] cluster. Also uses a c-type
cytochrome or O2 as acceptors. |
|---|
| Orthology |
KO: K08355 arsenite oxidase small subunit
KO: K08356 arsenite oxidase large subunit |
|---|
| Genes |
VSP: VS_II0658 VS_II0659
BMU: Bmul_5678 Bmul_5679 Bmul_5703 Bmul_5704
BMJ: BMULJ_05810(asoA) BMULJ_05811(asoB) BMULJ_05832(asoB)
BMULJ_05833(asoA)
RFR: Rfer_3084 Rfer_3085
HAR: HEAR0478(aoxB) HEAR0479(aoxA)
NHA: Nham_4426 Nham_4427
XAU: Xaut_3949 Xaut_3950
CPB: Cphamn1_2364 Cphamn1_2365
CLI: Clim_0382 Clim_0383
CAU: Caur_1209 Caur_1210
CAG: Cagg_0377 Cagg_0378
CHL: Chy400_1322 Chy400_1323
TTJ: TTHB127 TTHB128
APE: APE_2556.1 APE_2563
 |
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Reference
Authors
Title
Journal
Organism
|
1 [PMID:1331097]
Anderson GL, Williams J, Hille R.
The purification and characterization of arsenite oxidase from
Alcaligenes faecalis, a molybdenum-containing hydroxylase.
J. Biol. Chem. 267 (1992) 23674-82.
Alcaligenes faecalis |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:11250197]
Ellis PJ, Conrads T, Hille R, Kuhn P.
Crystal structure of the 100 kDa arsenite oxidase from Alcaligenes
faecalis in two crystal forms at 1.64 A and 2.03 A.
Structure. (Camb). 9 (2001) 125-32.
Alcaligenes faecalis |
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| Other DBs |
ExplorEnz - The Enzyme Database: 1.20.98.1
IUBMB Enzyme Nomenclature: 1.20.98.1
ExPASy - ENZYME nomenclature database: 1.20.98.1
UM-BBD (Biocatalysis/Biodegradation Database): 1.20.98.1
BRENDA, the Enzyme Database: 1.20.98.1
CAS: 146907-46-2 |
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