KEGG   ENZYME: 1.20.99.1Help
Entry
EC 1.20.99.1                Enzyme                                 

Name
arsenate reductase (donor);
arsenate:(acceptor) oxidoreductase
Class
Oxidoreductases;
Acting on phosphorus or arsenic in donors;
With other, unknown, acceptors
BRITE hierarchy
Sysname
arsenate:acceptor oxidoreductase
Reaction(IUBMB)
arsenite + acceptor = arsenate + reduced acceptor [RN:R05752]
Reaction(KEGG)
Substrate
arsenite [CPD:C06697];
acceptor [CPD:C00028]
Product
arsenate [CPD:C11215];
reduced acceptor [CPD:C00030]
Comment
Benzyl viologen can act as an acceptor. Unlike EC 1.20.4.1, arsenate reductase (glutaredoxin), reduced glutaredoxin cannot serve as a reductant.
History
EC 1.20.99.1 created 2000 as EC 1.97.1.6, transferred 2001 to EC 1.20.99.1
Reference
1  [PMID:9738904]
  Authors
Krafft T, Macy JM.
  Title
Purification and characterization of the respiratory arsenate reductase of Chrysiogenes arsenatis.
  Journal
Eur. J. Biochem. 255 (1998) 647-53.
Reference
2  [PMID:10649963]
  Authors
Radabaugh TR, Aposhian HV.
  Title
Enzymatic reduction of arsenic compounds in mammalian systems: reduction of arsenate to arsenite by human liver arsenate reductase.
  Journal
Chem. Res. Toxicol. 13 (2000) 26-30.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
146907-46-2

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