KEGG   ENZYME: 1.3.1.103Help
Entry
EC 1.3.1.103                Enzyme                                 

Name
2-haloacrylate reductase;
CAA43 (gene name)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(S)-2-chloropropanoate:NADP+ oxidoreductase
Reaction(IUBMB)
(S)-2-chloropropanoate + NADP+ = 2-chloroacrylate + NADPH + H+ [RN:R10418]
Reaction(KEGG)
Substrate
(S)-2-chloropropanoate [CPD:C20608];
NADP+ [CPD:C00006]
Product
2-chloroacrylate [CPD:C20609];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme acts in the degradation pathway of unsaturated organohalogen compounds by the bacterium Burkholderia sp. WS.
History
EC 1.3.1.103 created 2013
Reference
1  [PMID:15781461]
  Authors
Kurata A, Kurihara T, Kamachi H, Esaki N
  Title
2-Haloacrylate reductase, a novel enzyme of the medium chain dehydrogenase/reductase superfamily that catalyzes the reduction of a carbon-carbon double bond of unsaturated organohalogen compounds.
  Journal
J. Biol. Chem. 280 (2005) 20286-91.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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