KEGG   ENZYME: 1.3.1.11Help
Entry
EC 1.3.1.11                 Enzyme                                 

Name
2-coumarate reductase;
melilotate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
3-(2-hydroxyphenyl)propanoate:NAD+ oxidoreductase
Reaction(IUBMB)
3-(2-hydroxyphenyl)propanoate + NAD+ = 2-coumarate + NADH + H+ [RN:R03709]
Reaction(KEGG)
Substrate
3-(2-hydroxyphenyl)propanoate [CPD:C01198];
NAD+ [CPD:C00003]
Product
2-coumarate [CPD:C01772];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.3.1.11 created 1972
Pathway
Phenylalanine metabolism
Microbial metabolism in diverse environments
Reference
1
  Authors
Levy, C.C. and Weinstein, G.D.
  Title
The metabolism of coumarin by a microorganism. II. The reduction of o-coumaric acid to melilotic acid.
  Journal
Biochemistry 3 (1964) 1944-1947.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37251-10-8

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