KEGG   ENZYME: 1.3.1.13Help
Entry
EC 1.3.1.13                 Enzyme                                 
Name
prephenate dehydrogenase (NADP+);
prephenate dehydrogenase;
prephenate (nicotinamide adenine dinucleotide phosphate) dehydrogenase;
prephenate dehydrogenase (NADP)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
prephenate:NADP+ oxidoreductase (decarboxylating)
Reaction(IUBMB)
prephenate + NADP+ = 4-hydroxyphenylpyruvate + CO2 + NADPH [RN:R01730]
Reaction(KEGG)
Substrate
prephenate [CPD:C00254];
NADP+ [CPD:C00006]
Product
4-hydroxyphenylpyruvate [CPD:C01179];
CO2 [CPD:C00011];
NADPH [CPD:C00005]
Pathway
Phenylalanine, tyrosine and tryptophan biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K00211  
prephenate dehydrogenase (NADP+)
Genes
SCE: 
YBR166C(TYR1)
AGO: 
ERC: 
KLA: 
LTH: 
PPA: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0B01830(NCAS0B01830)
NDI: 
NDAI_0C05850(NDAI0C05850)
TPF: 
TPHA_0I01630(TPHA0I01630)
TBL: 
TBLA_0E04010(TBLA0E04010)
TDL: 
TDEL_0A05400(TDEL0A05400)
KAF: 
KAFR_0G02120(KAFR0G02120)
DHA: 
DEHA2G18414g
PIC: 
PICST_52223(TYR1)
PGU: 
PGUG_02400
LEL: 
LELG_04218
CAL: 
CaO19.12075(TYR1) CaO19.4605(TYR1)
CTP: 
CTRG_00228
CDU: 
CD36_41770
COT: 
CORT_0E00770
YLI: 
YALI0F17644g
CLU: 
CLUG_05025
NCR: 
NCU00468
SMP: 
SMAC_01902
PAN: 
PODANSg5004
TTT: 
THITE_2119199
MTM: 
MYCTH_2304552
MGR: 
MGG_05276
FGR: 
FG04139.1
NHE: 
NECHADRAFT_62071
VAL: 
VDBG_06623
SSL: 
SS1G_00089
BFU: 
BC1G_06216
ANI: 
AN5959.2
NFI: 
NFIA_085830
AFM: 
AFUA_2G10450
AOR: 
AOR_1_1008054(AO090011000595)
AFV: 
AFLA_044160
ACT: 
ACLA_069470
PCS: 
Pc22g20660
CIM: 
CIMG_04349
CPW: 
CPC735_073810
PBL: 
PAAG_01432
URE: 
UREG_01596
ABE: 
ARB_05782
TVE: 
TRV_04459
AJE: 
HCAG_08076
PNO: 
SNOG_02089
PTE: 
PTT_08159
ZTR: 
MYCGRDRAFT_108107
TML: 
GSTUM_00004491001
SPO: 
SPCC1494.04c(tyr1)
CNE: 
CNK03330
CNB: 
CNBK0170
CGI: 
CGB_K0270C
LBC: 
LACBIDRAFT_248404
CCI: 
CC1G_15508
SCM: 
SCHCODRAFT_77761
UMA: 
UM04182.1
MGL: 
MGL_4145 MGL_4163
PGR: 
PGTG_02942
PSN: 
Pedsa_2150
LBY: 
Lbys_1216
EOL: 
Emtol_3875
 » show all
Taxonomy
Reference
1  [PMID:4379953]
  Authors
Gamborg OL, Keeley FW.
  Title
Aromatic metabolism in plants. I. A study of the prephenate dehydrogenase from bean plants.
  Journal
Biochim. Biophys. Acta. 115 (1966) 65-72.
  Organism
Phaseolus vulgaris, Phaseolus coccineus, Phaseolus aureus, Vicia faba
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37251-11-9
DBGET integrated database retrieval system