KEGG   ENZYME: 1.3.1.13Help
Entry
EC 1.3.1.13                 Enzyme                                 

Name
prephenate dehydrogenase (NADP+);
prephenate dehydrogenase;
prephenate (nicotinamide adenine dinucleotide phosphate) dehydrogenase;
prephenate dehydrogenase (NADP)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
prephenate:NADP+ oxidoreductase (decarboxylating)
Reaction(IUBMB)
prephenate + NADP+ = 4-hydroxyphenylpyruvate + CO2 + NADPH [RN:R01730]
Reaction(KEGG)
Substrate
prephenate [CPD:C00254];
NADP+ [CPD:C00006]
Product
4-hydroxyphenylpyruvate [CPD:C01179];
CO2 [CPD:C00011];
NADPH [CPD:C00005]
History
EC 1.3.1.13 created 1972
Pathway
Phenylalanine, tyrosine and tryptophan biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Biosynthesis of antibiotics
Orthology
K00211  
prephenate dehydrogenase (NADP+)
Genes
SCE: 
YBR166C(TYR1)
AGO: 
ERC: 
KLA: 
LTH: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0B01830(NCAS0B01830)
NDI: 
NDAI_0C05850(NDAI0C05850)
TPF: 
TPHA_0I01630(TPHA0I01630)
TBL: 
TBLA_0E04010(TBLA0E04010)
TDL: 
TDEL_0A05400(TDEL0A05400)
KAF: 
KAFR_0G02120(KAFR0G02120)
PPA: 
DHA: 
PIC: 
PGU: 
SPAA: 
LEL: 
CAL: 
CTP: 
COT: 
CDU: 
CTEN: 
YLI: 
CLU: 
NCR: 
NTE: 
NEUTE1DRAFT63778(NEUTE1DRAFT_63778)
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
FPU: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
VDA: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_1008054(AO090011000595)
ANG: 
ANI_1_840024(An02g06120)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
PBN: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
TMS: 
PCO: 
SHS: 
HIR: 
PSQ: 
ADL: 
FME: 
GTR: 
LBC: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT122388(AGABI1DRAFT_122388)
ABV: 
AGABI2DRAFT226049(AGABI2DRAFT_226049)
CPUT: 
SLA: 
WSE: 
WIC: 
UMA: 
PFP: 
MGL: 
PGR: 
MLR: 
PEP: 
PSN: 
LBY: 
EOL: 
 » show all
Taxonomy
Reference
1  [PMID:4379953]
  Authors
Gamborg OL, Keeley FW.
  Title
Aromatic metabolism in plants. I. A study of the prephenate dehydrogenase from bean plants.
  Journal
Biochim. Biophys. Acta. 115 (1966) 65-72.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37251-11-9

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