KEGG   ENZYME: 1.3.1.18Help
Entry
EC 1.3.1.18                 Enzyme                                 

Name
kynurenate-7,8-dihydrodiol dehydrogenase;
7,8-dihydro-7,8-dihydroxykynurenate dehydrogenase;
7,8-dihydroxykynurenic acid 7,8-diol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
7,8-dihydro-7,8-dihydroxykynurenate:NAD+ oxidoreductase
Reaction(IUBMB)
7,8-dihydro-7,8-dihydroxykynurenate + NAD+ = 7,8-dihydroxykynurenate + NADH + H+ [RN:R03251]
Reaction(KEGG)
Substrate
7,8-dihydro-7,8-dihydroxykynurenate [CPD:C01249];
NAD+ [CPD:C00003]
Product
7,8-dihydroxykynurenate [CPD:C01111];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.3.1.18 created 1972
Pathway
Tryptophan metabolism
Reference
1  [PMID:13984873]
  Authors
TANIUCHI H, HAYAISHI O.
  Title
Studies on the metabolism of kynurenic acid. III. Enzymatic formation of 7,8-dihydroxykynurenic acid from kynurenic acid.
  Journal
J. Biol. Chem. 238 (1963) 283-93.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37255-30-4

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