| Entry |
|
|---|
| Name |
2-enoate reductase;
enoate reductase |
|---|
| Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
butanoate:NAD+ Delta2-oxidoreductase |
|---|
| Reaction(IUBMB) |
butanoate + NAD+ = 2-butenoate + NADH + H+ [RN:R01689] |
|---|
| Reaction(KEGG) |
R01689;
(other) R02252
 |
|---|
| Substrate |
butanoate [CPD:C00246];
NAD+ [CPD:C00003] |
|---|
| Product |
2-butenoate [CPD:C01771];
NADH [CPD:C00004];
H+ [CPD:C00080] |
|---|
| Cofactor |
FAD [CPD:C00016];
Iron [CPD:C00023];
Sulfur [CPD:C00087];
Iron-sulfur [CPD:C00824] |
|---|
| Comment |
An iron-sulfur-flavoprotein (FAD). Acts (in the reverse direction)
on a wide range of alkyl and aryl alphabeta-unsaturated carboxylate
ions; 2-butenoate was the best substrate tested. |
|---|
| Pathway |
ec00360 Phenylalanine metabolism |
|---|
| Orthology |
K10797 2-enoate reductase |
|---|
| Genes |
DDA: Dd703_1770
VFM: VFMJ11_A0422
SVO: SVI_1286
CAC: CA_C3371
CNO: NT01CX_0026
CBO: CBO2166(fldZ)
CBA: CLB_2105(enr)
CBH: CLC_2109(enr)
CBY: CLM_2376(enr)
CBL: CLK_1618(enr)
CBK: CLL_A1978
CBB: CLD_2412(enr)
CBI: CLJ_B2374(enr)
CBF: CLI_2212(enr)
CBE: Cbei_1927
CKL: CKL_0743
CKR: CKR_0664
MTA: Moth_2056
NTH: Nther_1849
PAK: HMPREF0675_4609
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:477658]
Tischer W, Bader J, Simon H.
Purification and some properties of a hitherto-unknown enzyme
reducing the carbon-carbon double bond of alpha, beta-unsaturated
carboxylate anions.
Eur. J. Biochem. 97 (1979) 103-12.
Clostridium kluyveri [GN:ckl], Clostridium sp. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.3.1.31
IUBMB Enzyme Nomenclature: 1.3.1.31
ExPASy - ENZYME nomenclature database: 1.3.1.31
BRENDA, the Enzyme Database: 1.3.1.31
CAS: 70712-51-5 |
|---|
