KEGG   ENZYME: 1.3.1.44Help
Entry
EC 1.3.1.44                 Enzyme                                 

Name
trans-2-enoyl-CoA reductase (NAD+);
trans-2-enoyl-CoA reductase (NAD+)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
acyl-CoA:NAD+ trans-2-oxidoreductase
Reaction(IUBMB)
acyl-CoA + NAD+ = trans-didehydroacyl-CoA + NADH + H+ [RN:R00384]
Reaction(KEGG)
Substrate
acyl-CoA [CPD:C00040];
NAD+ [CPD:C00003]
Product
trans-didehydroacyl-CoA [CPD:C00658];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme from Euglena gracilis acts on crotonoyl-CoA and, more slowly, on trans-hex-2-enoyl-CoA and trans-oct-2-enoyl-CoA.
History
EC 1.3.1.44 created 1989
Pathway
ec00650  Butanoate metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K00209  enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+)
Genes
ECLI: ECNIH5_17550
ECLA: ECNIH3_17630
ECLC: ECR091_17565
ENR: H650_03745
KOM: HR38_29650
CFD: CFNIH1_03990
CBRA: A6J81_16945
CAF: AL524_03345
CIR: C2U53_10055
GQU: AWC35_24085
YPE: YPO4104
YPK: y4119
YPA: YPA_4149
YPN: YPN_3961
YPM: YP_4011
YPZ: YPZ3_3519
YPD: YPD4_3612
YPX: YPD8_3618
YPH: YPC_4625
YPW: CH59_2061
YPJ: CH55_2786
YPV: BZ15_3598
YPL: CH46_944
YPS: YPTB3950
YPO: BZ17_2626
YPY: YPK_4244
YPB: YPTS_4200
YPQ: DJ40_2454
YPU: BZ21_3312
YPR: BZ20_2152
YPC: BZ23_3584
YPF: BZ19_3421
YEN: YE4179
YEY: Y11_29991
YEW: CH47_3544
YET: CH48_1641
YAL: AT01_2511
YFR: AW19_3288
YIN: CH53_1737
YKR: CH54_2502
YRO: CH64_2556
SPE: Spro_1949
SPLY: Q5A_009815
SSZ: SCc_447(fadH)
SMAF: D781_2172
SMAR: SM39_1424
SERF: L085_18945
RAA: Q7S_24276
ETA: ETA_17430
EPY: EpC_18330
EAM: EAMY_1757
EAY: EAM_1724
EBI: EbC_22580
MMK: MU9_3082
ETR: ETAE_1876
ETD: ETAF_1690
ETE: ETEE_3920
XFA: XF_1835
XFT: PD_1032
XCC: XCC0115
XCB: XC_0119
XCP: XCR_0135
XCV: XCV0120
XAX: XACM_0118
XAC: XAC0141
XOO: XOO0027
XOM: XOO0026(XOO0026)
XOP: PXO_03458
XOR: XOC_0167
XAL: XALC_0021
XPH: XppCFBP6546_11220(XppCFBP6546P_11220)
SML: Smlt2015
SMT: Smal_1619
SMZ: SMD_1813
PSUW: WQ53_10060
PSD: DSC_01770
LEZ: GLE_0533
LEM: LEN_4374(fabI)
DKO: I596_2167
VCH: VCA0784
VFI: VF_0888
PPR: PBPRA2423(PD1032) PBPRA2527(XCC0115)
PAE: PA2950
PAEV: N297_3055
PAEI: N296_3055
PAEP: PA1S_10645
PAEM: U769_10185
PAEL: T223_10660
PAEG: AI22_23225
PAEC: M802_3052
PAEO: M801_2920
PPU: PP_4635
PPF: Pput_4497
PPT: PPS_4463
PPI: YSA_03207
PPX: T1E_1542
PPUH: B479_22445
PPUT: L483_27635
PPUN: PP4_07240
PPUD: DW66_4854
PMON: X969_21985
PMOT: X970_21620
PFL: PFL_3335
PPRO: PPC_3359
PFS: PFLU_1621
PFB: VO64_4743
PEN: PSEEN4627
PSEM: TO66_13430
PSOS: POS17_2731
PANR: A7J50_1779
SON: SO_1800(fabV)
SDN: Sden_2487
SFR: Sfri_2585
SAZ: Sama_1230
SBL: Sbal_1610
SLO: Shew_2503
SPL: Spea_2676
SWD: Swoo_3107
SWP: swp_3256
SVO: SVI_2991
SPSW: Sps_01876
ILO: IL1051
CPS: CPS_0713
PHA: PSHAa2242
PAT: Patl_0451
PSM: PSM_A0844
PSEO: OM33_14400
PTN: PTRA_a2718(fabV)
PEA: PESP_a1049(fabV)
PSPO: PSPO_a2425(fabV)
PART: PARC_a2990(fabV)
PTU: PTUN_a3293(fabV)
PNG: PNIG_a2914(fabV)
PTD: PTET_a0957(fabV)
AMAL: I607_16415
AMAE: I876_16720
AMAO: I634_16670
AMAD: I636_16595
AMAI: I635_17340
AMAG: I533_16250
AMAC: MASE_16235
AAUS: EP12_16965
ASP: AOR13_51
GNI: GNIT_0762
GPS: C427_0467
PIN: Ping_0610
FBL: Fbal_2593
MVS: MVIS_2342
CJA: CJA_1411
SDE: Sde_2625
SAGA: M5M_18710
CBU: CBU_0270
CBD: CBUD_1824
CBG: CbuG_1738
CBC: CbuK_0462
LFA: LFA_0887
CYQ: Q91_0539
CSA: Csal_2823
HEL: HELO_1411
HAM: HALO1431
HBE: BEI_0481(fabV)
KKO: Kkor_0610
KGE: TQ33_1781
ACAV: VI35_00235
TAU: Tola_2687
OCE: GU3_06675
BMA: BMA0885
BMAL: DM55_2100
BMAE: DM78_2182
BMAQ: DM76_2075
BMAI: DM57_2939
BMAF: DM51_638
BMAZ: BM44_2366
BMAB: BM45_1931
BPS: BPSL2019
BPSE: BDL_555
BPSM: BBQ_1890
BPSU: BBN_2016
BPSD: BBX_2494
BPK: BBK_66
BPSH: DR55_3131
BPSA: BBU_725
BPSO: X996_2745
BUT: X994_1198
BTE: BTH_I2672
BTQ: BTQ_1352
BTJ: BTJ_1100
BTZ: BTL_2341
BTD: BTI_2416
BTV: BTHA_2540
BTHE: BTN_2427
BTHM: BTRA_2621
BTHA: DR62_2572
BTHL: BG87_2565
BOK: DM82_919
BOC: BG90_16
BVE: AK36_3125
BCN: Bcen_5407
BCJ: BCAM2650
BCEN: DM39_5213
BCEW: DM40_3246
BCEO: I35_6544
BAM: Bamb_4797
BMU: Bmul_3324
BMK: DM80_4705
BMUL: NP80_3219
BCT: GEM_5745
BCED: DM42_5327
BDL: AK34_3233
BCON: NL30_17025
BUB: BW23_3838
BLAT: WK25_28815
BTEI: WS51_09975
BSEM: WJ12_33150
BPSL: WS57_01055
BMEC: WJ16_31620
BSTG: WT74_31895
BGU: KS03_3964
BGO: BM43_6471
BUK: MYA_3271
BUL: BW21_2383
BXE: Bxe_A2198
BXB: DR64_4351
BFN: OI25_3615
PPNO: DA70_23345
PPNM: LV28_07365
PPUL: RO07_01555
PSPU: NA29_10105
PAPI: SG18_01690
MFA: Mfla_1676
PPO: PPM_1661(M1_1918) PPM_3737(M1_4127)
PRI: PRIO_5321
LHO: LOOC260_120310(ter)
PCE: PECL_1363
CARC: NY10_1787
JDA: BW727_101649(fabV)
CAC: CA_C0462
CAE: SMB_G0472
CAY: CEA_G0473
CPE: CPE2074
CPF: CPF_2331
CPR: CPR_2045
CBE: Cbei_2086
CBZ: Cbs_2086
CBEI: LF65_02396
CPAS: Clopa_3224
CPAT: CLPA_c16150(ccel)
CPAE: CPAST_c16150(ccel)
CCE: Ccel_2273
CCEL: CCDG5_1162
COO: CCU_20510
BPRL: CL2_10840
PFT: JBW_04265
SALU: DC74_5018
SALL: SAZ_26790
STRE: GZL_03844
STRM: M444_26220
SRW: TUE45_pSRc_0278(TUE45_pSRTUE45c_0278)
SLAU: SLA_7515
KFL: Kfla_5038
OTE: Oter_3891
CAA: Caka_1566
TDE: TDE0597
TPED: TPE_2028
BRM: Bmur_1267
BPW: WESB_2159
BIP: Bint_2694
LBA: Lebu_0716
FSC: FSU_1176
FLN: FLA_3939
PHE: Phep_2275
CHU: CHU_1071
FLM: MY04_3863
CHE: CAHE_0279
FJO: Fjoh_3464
FPS: FP1842
FIN: KQS_09375
EAO: BD94_2940
MPW: MPR_2757
WIN: WPG_3437
TMAR: MARIT_1974
AALG: AREALGSMS7_00271(fabV)
 » show all
Taxonomy
Reference
1  [PMID:3102464]
  Authors
Inui H, Miyatake K, Nakano Y, Kitaoka S.
  Title
Purification and some properties of short chain-length specific trans-2-enoyl-CoA reductase in mitochondria of Euglena gracilis.
  Journal
J. Biochem. (Tokyo). 100 (1986) 995-1000.
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.44
IUBMB Enzyme Nomenclature: 1.3.1.44
ExPASy - ENZYME nomenclature database: 1.3.1.44
BRENDA, the Enzyme Database: 1.3.1.44
CAS: 77649-64-0

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