KEGG   ENZYME: 1.3.1.56Help
Entry
EC 1.3.1.56                 Enzyme                                 

Name
cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase;
2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase
Reaction(IUBMB)
cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+ [RN:R05239]
Reaction(KEGG)
R05239;
(other) R05241
Show
Substrate
cis-3-phenylcyclohexa-3,5-diene-1,2-diol [CPD:C06589];
NAD+ [CPD:C00003]
Product
biphenyl-2,3-diol [CPD:C02526];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Catalyses the second step in the biphenyl degradation pathway in bacteria.
History
EC 1.3.1.56 created 2000
Pathway
Dioxin degradation
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K08690  
cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
Genes
PSD: 
BXE: 
Bxe_C1192(bphB)
BXB: 
DR64_8613(bphB)
PNA: 
ACK: 
CTES: 
PGV: 
RHA: 
ROP: 
Taxonomy
Reference
1  [PMID:8702262]
  Authors
Sylvestre M, Hurtubise Y, Barriault D, Bergeron J, Ahmad D.
  Title
Characterization of active recombinant 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase from Comamonas testosteroni B-356 and sequence of the encoding gene (bphB).
  Journal
Appl. Environ. Microbiol. 62 (1996) 2710-5.
  Sequence
Reference
2  [PMID:8048958]
  Authors
Fukuda M, Yasukochi Y, Kikuchi Y, Nagata Y, Kimbara K, Horiuchi H, Takagi M, Yano K.
  Title
Identification of the bphA and bphB genes of Pseudomonas sp. strains KKS102 involved in degradation of biphenyl and polychlorinated biphenyls.
  Journal
Biochem. Biophys. Res. Commun. 202 (1994) 850-6.
Reference
3  [PMID:8344527]
  Authors
Hofer B, Eltis LD, Dowling DN, Timmis KN.
  Title
Genetic analysis of a Pseudomonas locus encoding a pathway for biphenyl/polychlorinated biphenyl degradation.
  Journal
Gene. 130 (1993) 47-55.
  Sequence
[bxe:Bxe_C1192]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 

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