KEGG   ENZYME: 1.3.1.64Help
Entry
EC 1.3.1.64                 Enzyme                                 

Name
phthalate 4,5-cis-dihydrodiol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate:NAD+ oxidoreductase
Reaction(IUBMB)
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+ = 4,5-dihydroxyphthalate + NADH + H+ [RN:R05275]
Reaction(KEGG)
Substrate
cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate [CPD:C04783];
NAD+ [CPD:C00003]
Product
4,5-dihydroxyphthalate [CPD:C03233];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the phthalate degradation pathway in bacteria.
History
EC 1.3.1.64 created 2000
Pathway
Polycyclic aromatic hydrocarbon degradation
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K18067  
phthalate 4,5-cis-dihydrodiol dehydrogenase
Genes
HAM: 
RPF: 
CNC: 
BVI: 
BMU: 
BMK: 
BYI: 
BUO: 
BUE: 
BPT: 
BHZ: 
POL: 
PNA: 
VEI: 
DEL: 
CTT: 
CTES: 
CID: 
 » show all
Taxonomy
Reference
1  [PMID:3805038]
  Authors
Batie CJ, LaHaie E, Ballou DP.
  Title
Purification and characterization of phthalate oxygenase and phthalate oxygenase reductase from Pseudomonas cepacia.
  Journal
J. Biol. Chem. 262 (1987) 1510-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 

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