| Entry |
|
|---|
| Name |
cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate
dehydrogenase |
|---|
| Class |
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate:NAD(P)+
oxidoreductase (decarboxylating) |
|---|
| Reaction(IUBMB) |
cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate +
NAD(P)+ = 4-methylcatechol + NAD(P)H + CO2 [RN:R05292 R05293] |
|---|
| Reaction(KEGG) |
R05292 R05293
 |
|---|
| Substrate |
cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate
[CPD:C06729];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006] |
|---|
| Product |
4-methylcatechol [CPD:C06730];
NADH [CPD:C00004];
NADPH [CPD:C00005];
CO2 [CPD:C00011] |
|---|
| Comment |
Involved in the p-xylene degradation pathway in bacteria. |
|---|
| Pathway |
PATH: ec00622 Toluene and xylene degradation
PATH: ec01100 Metabolic pathways |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:3711022]
Whited GM, McCombie WR, Kwart LD, Gibson DT.
Identification of cis-diols as intermediates in the oxidation of
aromatic acids by a strain of Pseudomonas putida that contains a TOL
plasmid.
J. Bacteriol. 166 (1986) 1028-39.
Pseudomonas putida |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.3.1.67
IUBMB Enzyme Nomenclature: 1.3.1.67
ExPASy - ENZYME nomenclature database: 1.3.1.67
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.67
BRENDA, the Enzyme Database: 1.3.1.67 |
|---|
