KEGG   ENZYME: 1.3.7.4Help
Entry
EC 1.3.7.4                  Enzyme                                 

Name
phytochromobilin:ferredoxin oxidoreductase;
HY2;
PPhi B synthase;
phytochromobilin synthase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With an iron-sulfur protein as acceptor
BRITE hierarchy
Sysname
(3Z)-phytochromobilin:ferredoxin oxidoreductase
Reaction(IUBMB)
(3Z)-phytochromobilin + 2 oxidized ferredoxin = biliverdin IXalpha + 2 reduced ferredoxin [RN:R03678]
Reaction(KEGG)
Substrate
(3Z)-phytochromobilin [CPD:C05913];
oxidized ferredoxin [CPD:C00139]
Product
biliverdin IXalpha;
reduced ferredoxin [CPD:C00138]
Comment
Catalyses the two-electron reduction of biliverdin IXalpha. Can use [2Fe-2S] ferredoxins from a number of sources as acceptor but not the [4Fe-4S] ferredoxin from Clostridium pasteurianum. The isomerization of (3Z)-phytochromobilin to (3E)-phytochromobilin is thought to occur prior to covalent attachment to apophytochrome in the plant cell cytoplasm. Flavodoxins can be used instead of ferredoxin.
History
EC 1.3.7.4 created 2002
Pathway
Porphyrin and chlorophyll metabolism
Orthology
K08101  
phytochromobilin:ferredoxin oxidoreductase
Genes
ATH: 
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
MTR: 
CAM: 
ADU: 
LJA: 
Lj0g3v0050649.1(Lj0g3v0050649.1) Lj2g3v3337330.1(Lj2g3v3337330.1)
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
JCU: 
POP: 
POPTR_0001s26050g(POPTRDRAFT_172219) POPTR_0009s05270g(POPTRDRAFT_203221)
VVI: 
SLY: 
778324(AUREA)
SPEN: 
SOT: 
SIND: 
BVG: 
NNU: 
OSA: 
DOSA: 
Os01t0949400-01(Os01g0949400)
OBR: 
BDI: 
ATS: 
SBI: 
SORBI_03g045760(SORBIDRAFT_03g045760)
ZMA: 
542164(elm1)
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
PPP: 
 » show all
Taxonomy
Reference
1  [PMID:11283349]
  Authors
Frankenberg N, Mukougawa K, Kohchi T, Lagarias JC.
  Title
Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms.
  Journal
Plant. Cell. 13 (2001) 965-78.
Reference
2  [PMID:11500553]
  Authors
McDowell MT, Lagarias JC.
  Title
Purification and biochemical properties of phytochromobilin synthase from etiolated oat seedlings.
  Journal
Plant. Physiol. 126 (2001) 1546-54.
Reference
3  [PMID:8215388]
  Authors
Terry MJ, Wahleithner JA, Lagarias JC.
  Title
Biosynthesis of the plant photoreceptor phytochrome.
  Journal
Arch. Biochem. Biophys. 306 (1993) 1-15.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
138263-99-7

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