KEGG   ENZYME: 1.3.99.33Help
Entry
EC 1.3.99.33                Enzyme                                 

Name
urocanate reductase;
urdA (gene name)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With other acceptors
BRITE hierarchy
Sysname
dihydrourocanate:acceptor oxidoreductase
Reaction(IUBMB)
dihydrourocanate + acceptor = urocanate + reduced acceptor [RN:R10330]
Reaction(KEGG)
Substrate
dihydrourocanate [CPD:C20522];
acceptor [CPD:C00028]
Product
urocanate [CPD:C00785];
reduced acceptor [CPD:C00030]
Comment
The enzyme from the bacterium Shewanella oneidensis MR-1 contains a noncovalently-bound FAD and a covalently-bound FMN. It functions as part of an anaerobic electron transfer chain that utilizes urocanate as the terminal electron acceptor. The activity has been demonstrated with the artificial donor reduced methyl viologen.
Pathway
Histidine metabolism
Orthology
K17363  
urocanate reductase
Genes
SON: 
SBM: 
SBN: 
SBT: 
SPC: 
SHP: 
SSE: 
SPL: 
SHN: 
SHW: 
SHL: 
SWD: 
CTC: 
CPY: 
AMT: 
AOE: 
DDH: 
APR: 
NTH: 
CCU: 
ELE: 
SSM: 
IPO: 
 » show all
Taxonomy
Reference
1  [PMID:23078170]
  Authors
Bogachev AV, Bertsova YV, Bloch DA, Verkhovsky MI
  Title
Urocanate reductase: identification of a novel anaerobic respiratory pathway in Shewanella oneidensis MR-1.
  Journal
Mol. Microbiol. 86 (2012) 1452-63.
  Organism
Shewanella oneidensis [GN:son]
  Sequence
[son:SO_4620]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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