KEGG   ENZYME: 1.3.99.4Help
Entry
EC 1.3.99.4                 Enzyme                                 

Name
3-oxosteroid 1-dehydrogenase;
3-oxosteroid Delta1-dehydrogenase;
Delta1-dehydrogenase;
3-ketosteroid-1-en-dehydrogenase;
3-ketosteroid-Delta1-dehydrogenase;
1-ene-dehydrogenase;
3-oxosteroid:(2,6-dichlorphenolindophenol) Delta1-oxidoreductase;
4-en-3-oxosteroid:(acceptor)-1-en-oxido-reductase;
Delta1-steroid reductase;
3-oxosteroid:(acceptor) Delta1-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With other, unknown, acceptors
BRITE hierarchy
Sysname
3-oxosteroid:acceptor Delta1-oxidoreductase
Reaction(IUBMB)
a 3-oxosteroid + acceptor = a 3-oxo-Delta1-steroid + reduced acceptor [RN:R03748]
Reaction(KEGG)
Substrate
3-oxosteroid [CPD:C01876];
acceptor [CPD:C00028]
Product
3-oxo-Delta1-steroid [CPD:C02941];
reduced acceptor [CPD:C00030]
History
EC 1.3.99.4 created 1965
Pathway
Steroid degradation
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K05898  
3-oxosteroid 1-dehydrogenase
Genes
PPUU: 
SPL: 
SHL: 
PHA: 
PSHAa2133(tesH)
GPB: 
REU: 
REH: 
CNC: 
CTI: 
BUR: 
BCJ: 
BCT: 
BPE: 
BPC: 
CTT: 
MSD: 
PLA: 
NAR: 
NPP: 
SWI: 
LSP: 
MTU: 
Rv3537(kstD)
MTV: 
MTC: 
MRA: 
MTF: 
MTB: 
MTK: 
MTZ: 
MTG: 
MTE: 
MTUR: 
MTL: 
MTO: 
MTD: 
MTN: 
MTJ: 
MTUB: 
MTUC: 
MTUE: 
MTX: 
MTUH: 
MTUL: 
MBO: 
MBB: 
MBT: 
MBM: 
MBK: 
MAF: 
MCE: 
MCQ: 
MCV: 
MCX: 
MCZ: 
MPA: 
MAO: 
MAV: 
MIT: 
MIR: 
MIA: 
MID: 
MYO: 
MSM: 
MSG: 
MSA: 
MUL: 
MVA: 
MGI: 
MSP: 
MAB: 
MABB: 
MMV: 
MMC: 
MKM: 
MJL: 
MJD: 
MMI: 
MRH: 
MMM: 
MCB: 
MLI: 
MKN: 
ASD: 
AS9A_0923(kstD3)
CGT: 
NFA: 
NCY: 
NBR: 
RHA: 
RER: 
REY: 
ROP: 
ROP_44470(kstD3)
REQ: 
GBR: 
GPO: 
GPOL_c41290(kstD1) GPOL_c41370(kstD2)
GOR: 
KTR9_0802(kstD)
TPR: 
SMA: 
SCB: 
SDV: 
NCA: 
TCU: 
AMD: 
AMN: 
AMM: 
AMZ: 
AOI: 
STP: 
SAQ: 
AMS: 
CAI: 
CAU: 
CHL: 
TRO: 
 » show all
Taxonomy
Reference
1  [PMID:13673006]
  Authors
LEVY HR, TALALAY P.
  Title
Bacterial oxidation of steroids. II. Studies on the enzymatic mechanism of ring A dehydrogenation.
  Journal
J. Biol. Chem. 234 (1959) 2014-21.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
9029-04-3

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