KEGG   ENZYME: 1.4.1.16Help
Entry
EC 1.4.1.16                 Enzyme                                 
Name
diaminopimelate dehydrogenase;
meso-alpha,epsilon-diaminopimelate dehydrogenase;
meso-diaminopimelate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating)
Reaction(IUBMB)
meso-2,6-diaminoheptanedioate + H2O + NADP+ = L-2-amino-6-oxoheptanedioate + NH3 + NADPH + H+ [RN:R02755]
Reaction(KEGG)
Substrate
meso-2,6-diaminoheptanedioate [CPD:C00680];
H2O [CPD:C00001];
NADP+ [CPD:C00006]
Product
L-2-amino-6-oxoheptanedioate [CPD:C03871];
NH3 [CPD:C00014];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Pathway
Lysine biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K03340  
diaminopimelate dehydrogenase
Genes
PMR: 
PSI: 
MMK: 
PSJ: 
PRW: 
MBS: 
TGR: 
GPB: 
PUT: 
RFR: 
AJS: 
Ajs_2757
DIA: 
Dtpsy_2247
DAC: 
Daci_2479
DEL: 
DelCs14_4183
CTT: 
CtCNB1_3320
ADN: 
Alide_1487
ADK: 
Alide2_3439
HAR: 
HEAR2481
NII: 
Nit79A3_2698
CCO: 
CCC13826_1251
PCA: 
Pcar_2787
DDS: 
Ddes_1119
DIN: 
Selin_2063
AXL: 
AXY_06490(ddh)
LSP: 
Bsph_3035
GYM: 
GYMC10_4995
TCO: 
Theco_1094
SIV: 
SSIL_2217
THL: 
TEH_03760(ddh)
AUR: 
HMPREF9243_1274
CRN: 
CAR_c12320(ddh)
CTC: 
CTC02532
CNO: 
NT01CX_0433
CTH: 
Cthe_0922
CTX: 
Clo1313_1295
CBK: 
CLL_A3000
CBN: 
CbC4_2183
CBT: 
CLH_2749
CPY: 
Cphy_2659
CCE: 
Ccel_2533
CSH: 
Closa_0123
CSO: 
CLS_20310
CLB: 
Clo1100_0671
CCL: 
Clocl_2080
CAD: 
Curi_c28460(ddh)
CSS: 
Cst_c19600(ddh2)
CSD: 
Clst_1878
STH: 
STH1425
SWO: 
Swol_0940
DSY: 
DSY0242
DHD: 
Dhaf_0187
DDH: 
Desde_0169
DDL: 
Desdi_0152
BPB: 
bpr_I0298
BFI: 
CIY_14290
CLE: 
Clole_2654
RAL: 
Rumal_1291
RUM: 
CK1_20790
ROB: 
CK5_18050
RTO: 
RTO_26020
BPRS: 
CK3_21290
BPRL: 
CL2_13780
TEP: 
TepRe1_0343 TepRe1_2001
TAE: 
TEPIRE1_23030 TEPIRE1_3820
VPR: 
Vpar_0329
SSG: 
Selsp_0198
SRI: 
SELR_03300(ddh)
AFN: 
Acfer_0990
AIN: 
Acin_0942
ACL: 
ACL_0763
CGL: 
NCgl2528(Cgl2617)
CGB: 
cg2900(ddh)
CGU: 
WA5_2528(Ddh)
CGT: 
cgR_2525
CEF: 
CE2498(ddh)
CUR: 
cur_1936(ddh)
CUA: 
CU7111_1859(ddh)
CHN: 
A605_12020
AAI: 
AARI_01410(ddh)
MLU: 
Mlut_19060
BFA: 
Bfae_19670
MCU: 
HMPREF0573_10717
CCU: 
Ccur_13630
ELE: 
Elen_0753
EYY: 
EGYY_05500
BTH: 
BT_1979
BFR: 
BF3690
BFS: 
BF3481
BFG: 
BF638R_3505
BVU: 
BVU_1659
BHL: 
Bache_3222
BSA: 
Bacsa_2579
PGI: 
PG0806
PGN: 
PGN_0830
PGT: 
PGTDC60_1925
PAH: 
Poras_1203
PDI: 
BDI_3565
OSP: 
Odosp_1546
TFO: 
BFO_1811
PRU: 
PRU_2042
PMZ: 
HMPREF0659_A6106
PDN: 
HMPREF9137_1783
PIT: 
PIN17_A1039
PDT: 
Prede_0951
PSN: 
Pedsa_1251
FSU: 
Fisuc_0002
FSC: 
FSU_0395
OTE: 
Oter_4154
AMU: 
Amuc_0581
EMI: 
Emin_1048
TTA: 
Theth_1310
NDE: 
NIDE3823
MVN: 
Mevan_0344
MHI: 
Mhar_0438
 » show all
Taxonomy
Reference
1  [PMID:10904]
  Authors
Misono H, Togawa H, Yamamoto T, Soda K.
  Title
Occurrence of meso-alpha, epsilon-diaminopimelate dehydrogenase in Bacillus sphaericus.
  Journal
Biochem. Biophys. Res. Commun. 72 (1976) 89-93.
  Organism
Bacillus sphaericus
Reference
2  [PMID:762012]
  Authors
Misono H, Togawa H, Yamamoto T, Soda K.
  Title
Meso-alpha,epsilon-diaminopimelate D-dehydrogenase: distribution and the reaction product.
  Journal
J. Bacteriol. 137 (1979) 22-7.
  Organism
Corynebacterium glutamicum [GN:cgl cgb], Bacillus sphaericus, Brevibacterium sp., Proteus vulgaris
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
60894-21-5
DBGET integrated database retrieval system