KEGG   ENZYME: 1.4.1.5Help
Entry
EC 1.4.1.5                  Enzyme                                 

Name
L-amino-acid dehydrogenase
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
L-amino-acid:NAD+ oxidoreductase (deaminating)
Reaction(IUBMB)
an L-amino acid + H2O + NAD+ = a 2-oxo carboxylate + NH3 + NADH + H+ [RN:R01258]
Reaction(KEGG)
R01258;
(other) R00145 R00146
Show
Substrate
L-amino acid [CPD:C00151];
H2O [CPD:C00001];
NAD+ [CPD:C00003]
Product
2-oxo carboxylate [CPD:C00161];
NH3 [CPD:C00014];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Acts on aliphatic amino acids.
History
EC 1.4.1.5 created 1961
Reference
1  [PMID:14910739]
  Authors
NISMAN B, MAGER J.
  Title
Diphosphopyridine nucleotide and phosphate requirement for oxidation of amino-acids by cell-free extracts of obligate anaerobes.
  Journal
Nature. 169 (1952) 243-4.
  Organism
Clostridia sporogenes, Clostridia saccharobutyricum
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9029-13-4

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