KEGG   ENZYME: 1.4.1.8Help
Entry
EC 1.4.1.8                  Enzyme                                 

Name
valine dehydrogenase (NADP+);
valine dehydrogenase (nicotinanide adenine dinucleotide phosphate);
valine dehydrogenase (NADP)
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
L-valine:NADP+ oxidoreductase (deaminating)
Reaction(IUBMB)
L-valine + H2O + NADP+ = 3-methyl-2-oxobutanoate + NH3 + NADPH + H+ [RN:R01212]
Reaction(KEGG)
R01212;
(other) R00145 R00146
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Substrate
L-valine [CPD:C00183];
H2O [CPD:C00001];
NADP+ [CPD:C00006]
Product
3-methyl-2-oxobutanoate [CPD:C00141];
NH3 [CPD:C00014];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.4.1.8 created 1972
Reference
1  [PMID:6005410]
  Authors
Kagan ZS, Kretovich WL, Polyakov WA.
  Title
Biosynthesis of valine by reductive amination of its keto analogue in plants.
  Journal
Enzymologia. 30 (1966) 343-66.
Reference
2  [PMID:4385962]
  Authors
Kagan ZS, Poliakov VA, Kretovich VL.
  Title
[Soluble valine dehydrogenase from roots of plant seedings]
  Journal
Biokhimiia. 33 (1968) 89-96.
Reference
3  [PMID:4389825]
  Authors
Kagan ZS, Poliakov VA, Kretovich VL.
  Title
[Purification and properties of valine dehydrogenase]
  Journal
Biokhimiia. 34 (1969) 59-65.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37255-39-3

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