KEGG   ENZYME: 1.4.3.21Help
Entry
EC 1.4.3.21                 Enzyme                                 

Name
primary-amine oxidase;
amine oxidase (ambiguous);
amine oxidase (copper-containing);
amine oxidase (pyridoxal containing) (incorrect);
benzylamine oxidase (incorrect);
CAO (ambiguous);
copper amine oxidase (ambiguous);
Cu-amine oxidase (ambiguous);
Cu-containing amine oxidase (ambiguous);
diamine oxidase (incorrect);
diamino oxhydrase (incorrect);
histamine deaminase (ambiguous);
histamine oxidase (ambiguous);
monoamine oxidase (ambiguous);
plasma monoamine oxidase (ambiguous);
polyamine oxidase (ambiguous);
semicarbazide-sensitive amine oxidase (ambiguous);
SSAO (ambiguous)
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
primary-amine:oxygen oxidoreductase (deaminating)
Reaction(IUBMB)
RCH2NH2 + H2O + O2 = RCHO + NH3 + H2O2 [RN:R01853]
Reaction(KEGG)
Substrate
RCH2NH2 [CPD:C00375];
H2O [CPD:C00001];
O2 [CPD:C00007]
Product
RCHO [CPD:C00071];
NH3 [CPD:C00014];
H2O2 [CPD:C00027]
Comment
A group of enzymes that oxidize primary monoamines but have little or no activity towards diamines, such as histamine, or towards secondary and tertiary amines. They are copper quinoproteins (2,4,5-trihydroxyphenylalanine quinone) and, unlike EC 1.4.3.4, monoamine oxidase, are sensitive to inhibition by carbonyl-group reagents, such as semicarbazide. In some mammalian tissues the enzyme also functions as a vascular-adhesion protein (VAP-1).
History
EC 1.4.3.21 created 2007 (EC 1.4.3.6 created 1961, part-incorporated 2008)
Pathway
Glycine, serine and threonine metabolism
Tyrosine metabolism
Phenylalanine metabolism
beta-Alanine metabolism
Isoquinoline alkaloid biosynthesis
Tropane, piperidine and pyridine alkaloid biosynthesis
Metabolic pathways
Biosynthesis of secondary metabolites
Orthology
K00276  
primary-amine oxidase
Genes
HSA: 
314(AOC2) 8639(AOC3)
PTR: 
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
100431015(AOC2) 708053 711820(AOC3)
MCF: 
102140322(AOC3) 102141512(AOC2)
CSAB: 
RRO: 
CJC: 
100392303(AOC2) 100392670 100413669(AOC3)
SBQ: 
101047774
MMU: 
11754(Aoc3) 237940(Aoc2)
RNO: 
29473(Aoc3)
CGE: 
100762635(Aoc2) 100762926
NGI: 
103735920(Aoc2) 103735921(Aoc3)
HGL: 
101709673(Aoc3) 101721663
CCAN: 
109687315 109687342(Aoc2) 109687344(Aoc3)
OCU: 
100346229 100353463
TUP: 
102490650(AOC2) 102491341(AOC3) 102491763
CFA: 
480511(AOC3) 490957(AOC2)
AML: 
100474209(AOC3) 100481510(AOC2)
UMR: 
103672591(AOC2) 103672631(AOC3) 103672632
FCA: 
101080592(AOC2) 101092904(AOC3) 101093157
PTG: 
102950796 102951108 102963389(AOC2)
AJU: 
106972577 106972620(AOC2) 106972622 106989756 106989832
BTA: 
100138645 100336082(AOC2) 281002(AOC3) 789307(SAO)
BOM: 
102267937 102273246(AOC3) 102273527(AOC2) 102287961
BIU: 
109573140 109573311 109573609 109573610 109573612 109573624
PHD: 
102319229(AOC2) 102319810(AOC3) 102329876 102342205
CHX: 
102168295(AOC3) 102168762(AOC2) 102169793 102170459 102182869 102184553 106501774
OAS: 
101103304 101106783(AOC2) 101112335(AOC3) 101112584 101113086 105605918 105605975
SSC: 
100520329(AOC3) 100520513(AOC2)
CFR: 
102514422(AOC3) 102514845(AOC2) 102522004
BACU: 
103000918 103001659 103011530 103012112(AOC2)
LVE: 
103076338(AOC2) 103076781(AOC3) 103080265
ECB: 
100065718(AOC3) 100065767 100630218(AOC2)
MYB: 
102254129(AOC2) 102255007(AOC3) 102256114
MYD: 
102758218 102758498 102758778(AOC2) 107185237
HAI: 
109378845 109378878 109378879 109395732 109395770(AOC2) 109395771(AOC3)
RSS: 
109439855 109440297 109440429 109442643 109455814(AOC2) 109455815
PALE: 
102897640 102898390(AOC3) 102898638(AOC2)
LAV: 
100673883 100675868(AOC2) 100676341(AOC3)
MDO: 
100011232(AOC2)
SHR: 
100916389(AOC3) 100931056(AOC2)
OAA: 
100089720
GGA: 
420015(AOC3)
MGP: 
100545760 100548064
CJO: 
107325298 107325299(AOC2)
APLA: 
101792066 101792268
TGU: 
101234248
GFR: 
102034973 102041321 106632201
FAB: 
101821363(AOC3)
PHI: 
102102104(AOC3) 102102284
CCW: 
104697770(AOC3)
FPG: 
101915227(AOC3) 101917818 101918169 106112940
FCH: 
102047909 102048083(AOC2) 102048254
CLV: 
102088654 102095916(AOC3)
AAM: 
106491791
ASN: 
102370307 102370538(AOC2) 102381970 102386770
AMJ: 
102568108(AOC3) 102576651 106737122
PSS: 
102463817 102464074(AOC3)
CMY: 
102935443 102935662 102944942
CPIC: 
101946562 101946984(AOC2)
ACS: 
100552532 103279214
PBI: 
103048487 103048718 103052671 103057770 103061474 103064670 103065944 103065948
GJA: 
107113693 107118705 107124965 107125068 107125235 107125401
XLA: 
108702003 108702723 446874(aoc3.L)
XTR: 
100497523(aoc2) 594972(aoc3)
DRE: 
541429(aoc2)
IPU: 
108276610
TRU: 
101069735
TNG: 
GSTEN00008440G001
LCO: 
104927167
MZE: 
101476241
OLA: 
101156175
XMA: 
102227558
CSEM: 
103393524 103393526
SASA: 
100194731(aoc2) 106601268
LCM: 
102347278 102366117 102366363(AOC3)
CMK: 
103172692
CRG: 
105332360
ATH: 
AT1G31670 AT1G31690 AT1G31710 AT1G62810(CuAO1) AT2G42490 AT3G43670 AT4G12290 AT4G14940(AO1)
ALY: 
ARALYDRAFT_313750 ARALYDRAFT_347467 ARALYDRAFT_352314 ARALYDRAFT_475070 ARALYDRAFT_484808 ARALYDRAFT_493397 ARALYDRAFT_890722 ARALYDRAFT_903619 ARALYDRAFT_905408 ARALYDRAFT_911616
CRB: 
CARUB_v10000307mg CARUB_v10002830mg CARUB_v10004333mg CARUB_v10008452mg CARUB_v10008490mg CARUB_v10019874mg CARUB_v10022684mg
EUS: 
EUTSA_v10006982mg EUTSA_v10007005mg EUTSA_v100163160m EUTSA_v100163161m EUTSA_v10023306mg EUTSA_v10024636mg EUTSA_v10028460mg
BRP: 
103833801 103833844 103848201 103849957 103858017 103865952 103868133 103871484
BNA: 
106355105 106355106 106365391 106370761 106377306 106388276 106391724 106395763 106396627 106396908 106398096 106402089 106421435 106428169 106439680 106439681 106447582
THJ: 
104803024 104808311 104808537 104809263 104813836 104814034 104818423
CIT: 
102610710 102611727 102618241 102623979 102624545 102625302 102628236 107178412
CIC: 
CICLE_v10004473mg CICLE_v10004484mg CICLE_v10004511mg CICLE_v10006554mg CICLE_v10006614mg CICLE_v10006722mg CICLE_v10018950mg CICLE_v10019032mg CICLE_v10030749mg
TCC: 
108661191 18602967 18602968 18602973 18602974 18603984 18606349 18606350 18609545
GRA: 
105764292 105785805 105788633 105789194 105789741 105792112 105796639 105797510 105800513
GHI: 
107886210 107894031 107895118 107920821 107920984 107922409 107927763 107927764 107928452 107928693 107931297 107946240 107949638 107963669
EGR: 
104414845 104414846 104414847 104417376 104417377 104417758 104433510 104441862 104443155
GMX: 
100778802 100781472 100783091 100798399 100798722 100799555 100800090 100802062 100802589 100804651 100817454 100817473 100819571 547524(PAO1) 548000(DAO)
PVU: 
PHAVU_002G150400g PHAVU_003G040500g PHAVU_003G064200g PHAVU_003G106200g PHAVU_003G204000g PHAVU_005G023500g PHAVU_005G023600g PHAVU_007G056200g PHAVU_007G056400g PHAVU_007G056500g PHAVU_007G056600g PHAVU_009G174800g
VRA: 
106753402 106759848 106762355 106762852 106777802 106780384 106780388 106780392 106780397 106780771
VAR: 
108324768 108325121 108325192 108325802 108329421 108331906 108334203 108334725 108343133
CCAJ: 
109791767 109797299 109797368 109797957 109800880 109805761 109807288 109807660 109812868 109813419
MTR: 
MTR_1g104550 MTR_1g104590 MTR_3g077080 MTR_3g080500 MTR_4g045887 MTR_4g098910 MTR_4g117610 MTR_4g117660 MTR_4g117670 MTR_5g033170 MTR_8g069505
CAM: 
101491487 101491799 101494680 101494998 101507021 101507416 101511923 101512543
ADU: 
107462776 107464920 107466862 107467072 107467100 107477883 107478926
AIP: 
107613021 107618244 107618246 107618247 107629396 107629880 107637855 107639382 107643313
LJA: 
Lj0g3v0086469.1(Lj0g3v0086469.1) Lj0g3v0161899.1(Lj0g3v0161899.1) Lj0g3v0161909.1(Lj0g3v0161909.1) Lj0g3v0161929.1(Lj0g3v0161929.1) Lj0g3v0278169.1(Lj0g3v0278169.1) Lj2g3v1242220.1(Lj2g3v1242220.1) Lj4g3v2376120.1(Lj4g3v2376120.1) Lj5g3v1414160.1(Lj5g3v1414160.1) Lj5g3v2046150.1(Lj5g3v2046150.1) Lj5g3v2046160.1(Lj5g3v2046160.1)
LANG: 
109328478 109333054 109343584 109344947 109352951 109355914 109362517
FVE: 
101298123 101298418 101303958 101305686 101307595 101308463 101309643 101311140
PPER: 
18777108 18777493 18790222 18790558 18791561 18792067
PMUM: 
103321853 103324275 103324291 103337259 103337929
MDM: 
103403902 103407292 103409872 103409894 103409897 103415219 103428571 103431132 103438321 103443458 103452038
PXB: 
103935980 103937550 103947299 103952965 103956666 103956668 103956669 103958325
ZJU: 
107418311 107419477 107421646 107423186 107423187 107423189 107423190 107423201 107423205 107428609
CSV: 
101204200 101210998 101212818 101213059 101221992 101222232 101222468
CMO: 
103482657 103482659 103491399 103491400 103491401 103502378
RCU: 
8261466 8261468 8261470 8261471 8272134 8272135 8273500 8278300
JCU: 
105631973 105632208 105638689 105640318 105644294 105644656 105645963 105646082
POP: 
POPTR_0001s07870g POPTR_0001s07880g POPTR_0008s15130g(POPTRDRAFT_766346) POPTR_0010s05570g(POPTRDRAFT_726235) POPTR_0010s09900g(POPTRDRAFT_882734) POPTR_0010s09910g(POPTRDRAFT_880464) POPTR_0010s09920g(POPTRDRAFT_231236) POPTR_0010s09930g POPTR_0012s08630g(POPTRDRAFT_570122) POPTR_0015s09450g(POPTRDRAFT_824697) POPTR_0569s00200g
VVI: 
100244323 100249520 100251211 100256366 100259696 100259834 100267280 100853400 109122587
SLY: 
101253199 101253862 101254319 101254423 101263760 101266123 543808(cuAO)
SPEN: 
107012994 107020357 107022669 107027112 107028398 107030442 107030474 107030611
SOT: 
102578904 102580758 102581835 102583802 102584319 102586410 102586593 102591556 102600413 102603512 102605322
INI: 
109153239 109160628 109160658 109162359 109172074 109175455 109175802 109186033
SIND: 
105157267 105164213 105164214 105171340 105171578 105171579 105172783 105179376
BVG: 
104884038 104891957 104892088 104892090 104892095 104892124 104894341 104897280
NNU: 
104591482 104593101 104596514 104602256 104611496
OSA: 
107276105 4335335 4336153 4340945 4343673(OJ1121_A05.21)
DOSA: 
Os02t0593100-00(Os02g0593100) Os04t0136200-00(Os04g0136200) Os04t0269600-01(Os04g0269600) Os04t0476100-01(Os04g0476100) Os06t0338200-01(Os06g0338200) Os06t0338700-00(Os06g0338700) Os07t0572050-00(Os07g0572050) Os07t0572100-01(Os07g0572100)
OBR: 
102700920 102702003 102708811 102710603 102717810 102722483
BDI: 
100824747 100837848 100845872
ATS: 
F775_04906 F775_10718 F775_21061 F775_52450
SBI: 
8056374 8068603 8069427
ZMA: 
100279491 100383438(pco118120) 103641531
SITA: 
101757997 101765584 101782360 101784250
PDA: 
103697515 103702015 103706132
EGU: 
105034269 105044125 105046503 105055420
MUS: 
103968460 103975076 103987137 103987620 103993259 103993955 103994655 103995027 103997609
ATR: 
18435143 18447660
SMO: 
SELMODRAFT_121227 SELMODRAFT_123165 SELMODRAFT_153358 SELMODRAFT_443642
PPP: 
PHYPADRAFT_141468 PHYPADRAFT_174842 PHYPADRAFT_177807 PHYPADRAFT_179471 PHYPADRAFT_190773
CRE: 
CHLREDRAFT_176519(AMX1) CHLREDRAFT_178662(AMX2)
VCN: 
VOLCADRAFT_84774(amx1)
MIS: 
MICPUN_56524(MAO)
CSL: 
COCSUDRAFT_29142
APRO: 
F751_0581
CME: 
CYME_CMI002C CYME_CMS002C CYME_CMT003C
GSL: 
Gasu_64640
AGO: 
AGOS_AGL073W
ERC: 
Ecym_7250
KLA: 
KLLA0E18371g
LTH: 
KLTH0D06996g
ZRO: 
ZYRO0B02112g
PPA: 
PAS_chr1-4_0441 PAS_chr2-1_0307 PAS_chr4_0621
DHA: 
DEHA2E02640g DEHA2G05698g
PIC: 
PICST_55523(AMO1) PICST_83878(AMO2)
PGU: 
PGUG_00111 PGUG_02914
SPAA: 
SPAPADRAFT_55057 SPAPADRAFT_60808
LEL: 
LELG_01290 LELG_01912
CAL: 
CAALFM_C203120WA(AMO1) CAALFM_C206700WA(AMO2)
CTP: 
CTRG_01313 CTRG_01793
COT: 
CORT_0A10990 CORT_0B05660
CDU: 
CD36_17890 CD36_21000
CTEN: 
CANTEDRAFT_101270 CANTEDRAFT_127768
YLI: 
YALI0C18315g YALI0C22792g
CLU: 
CLUG_00771 CLUG_05800
CAUR: 
QG37_05361 QG37_07057
NCR: 
NCU05518 NCU09406
NTE: 
NEUTE1DRAFT85409(NEUTE1DRAFT_85409) NEUTE1DRAFT87576(NEUTE1DRAFT_87576)
SMP: 
SMAC_00731 SMAC_05665 SMAC_08598
PAN: 
PODANSg1629 PODANSg1815 PODANSg2361 PODANSg2762
TTT: 
THITE_2110511 THITE_2117123
MTM: 
MYCTH_2308831 MYCTH_2311035
CTHR: 
CTHT_0016800 CTHT_0044710
MGR: 
MGG_03332 MGG_05808 MGG_09602 MGG_10751 MGG_13291 MGG_15019
TMN: 
UCRPA7_1072 UCRPA7_1165 UCRPA7_2182 UCRPA7_283 UCRPA7_5960 UCRPA7_6190
FGR: 
FGSG_01761 FGSG_02271 FGSG_02279 FGSG_03278 FGSG_10587 FGSG_10677 FGSG_12129 FGSG_13604
FPU: 
FPSE_00294 FPSE_00301 FPSE_00736 FPSE_03318 FPSE_05704 FPSE_06871 FPSE_08458
FVR: 
FVEG_04368 FVEG_08565 FVEG_09371 FVEG_10879 FVEG_11764 FVEG_11971 FVEG_12223 FVEG_13749 FVEG_13798 FVEG_15472
NHE: 
NECHADRAFT_104867 NECHADRAFT_34648 NECHADRAFT_54669 NECHADRAFT_55285 NECHADRAFT_63123 NECHADRAFT_66020 NECHADRAFT_72647 NECHADRAFT_72998 NECHADRAFT_78479 NECHADRAFT_84204 NECHADRAFT_93985 NECHADRAFT_94780 NECHADRAFT_94904 NECHADRAFT_98248
TRE: 
TRIREDRAFT_121156 TRIREDRAFT_122963
MAW: 
MAC_02145 MAC_02351 MAC_06392 MAC_06866 MAC_08480
MAJ: 
MAA_05085 MAA_06882 MAA_06939 MAA_08459 MAA_09819 MAA_11450
CMT: 
CCM_02614 CCM_05218 CCM_06912 CCM_08193
VAL: 
VDBG_00267 VDBG_02350 VDBG_02684 VDBG_06198 VDBG_08713 VDBG_09036 VDBG_09164 VDBG_09214
VDA: 
VDAG_02821 VDAG_03348 VDAG_06374 VDAG_07314 VDAG_07369 VDAG_08551
CFJ: 
CFIO01_00373 CFIO01_00821 CFIO01_01534 CFIO01_01780 CFIO01_01924 CFIO01_02243 CFIO01_05627 CFIO01_08053 CFIO01_08408 CFIO01_08978
ELA: 
UCREL1_2882 UCREL1_4952 UCREL1_5145 UCREL1_7095 UCREL1_7276
SSL: 
SS1G_04591 SS1G_11146 SS1G_12311
BFU: 
BC1G_00004 BC1G_14626
MBE: 
MBM_05980 MBM_08181 MBM_09344
PSCO: 
LY89DRAFT_582517 LY89DRAFT_588672 LY89DRAFT_602519 LY89DRAFT_628154 LY89DRAFT_640433 LY89DRAFT_704657 LY89DRAFT_741504 LY89DRAFT_745382
ANI: 
AN1586.2 AN2532.2 AN5690.2 AN6092.2 AN7641.2 AN8454.2
AFM: 
AFUA_1G13440 AFUA_3G00680 AFUA_3G14590 AFUA_5G01470 AFUA_5G07360 AFUA_7G04180 AFUA_7G08470
AOR: 
AOR_1_132064(AO090138000079) AOR_1_192174(AO090005000103) AOR_1_378054(AO090011000229) AOR_1_560114(AO090701000307) AOR_1_610154(AO090003000356) AOR_1_656034(AO090103000401) AOR_1_896114(AO090701000490)
ANG: 
ANI_1_154(An17g00010) ANI_1_156084(An09g01550) ANI_1_1910064(An07g06400) ANI_1_3000024(An02g10920) ANI_1_550114(An13g00710) ANI_1_80034(An03g00730)
AFV: 
AFLA_008350 AFLA_034620 AFLA_040370 AFLA_057610 AFLA_059590 AFLA_062970 AFLA_073450 AFLA_123940
ACT: 
ACLA_005880 ACLA_010630 ACLA_042070 ACLA_063240
NFI: 
NFIA_001270 NFIA_012060 NFIA_025150 NFIA_030980 NFIA_040640 NFIA_062690 NFIA_079900
PCS: 
Pc13g03350 Pc13g15940 Pc16g11200 Pc21g04560 Pc22g14860 Pc22g17240
PDP: 
PDIP_13870 PDIP_19340 PDIP_53010 PDIP_82510
CIM: 
CIMG_00216 CIMG_01680 CIMG_03782 CIMG_06108 CIMG_06868
CPW: 
CPC735_005320 CPC735_026690 CPC735_032690 CPC735_048000 CPC735_059480
PBL: 
PAAG_02065 PAAG_02222 PAAG_03755 PAAG_08658
PBN: 
PADG_05360 PADG_07263 PADG_11154 PADG_11456(PADG_02621) PADG_11457(PADG_02621) PADG_11571(PADG_03260)
URE: 
UREG_00310 UREG_03616 UREG_04256 UREG_05400 UREG_07502
ABE: 
ARB_04019 ARB_06355
TVE: 
TRV_05381 TRV_07431
AJE: 
HCAG_01864 HCAG_07191 HCAG_07301 HCAG_07466
PNO: 
SNOG_02686 SNOG_04089 SNOG_07379 SNOG_11787 SNOG_13882 SNOG_15326 SNOG_15329
PTE: 
PTT_08184 PTT_09107 PTT_10091 PTT_12464
BZE: 
COCCADRAFT_100853 COCCADRAFT_103700 COCCADRAFT_104234 COCCADRAFT_105158 COCCADRAFT_21929 COCCADRAFT_84263
BSC: 
COCSADRAFT_122608 COCSADRAFT_134423 COCSADRAFT_183317 COCSADRAFT_197311 COCSADRAFT_290377 COCSADRAFT_35183
BOR: 
COCMIDRAFT_100833 COCMIDRAFT_1598 COCMIDRAFT_2110 COCMIDRAFT_29138 COCMIDRAFT_33548
ZTR: 
MYCGRDRAFT_100462 MYCGRDRAFT_100872 MYCGRDRAFT_73347
PFJ: 
MYCFIDRAFT_135854 MYCFIDRAFT_211721 MYCFIDRAFT_56446
BCOM: 
BAUCODRAFT_576846 BAUCODRAFT_59376 BAUCODRAFT_69041
NPA: 
UCRNP2_10268 UCRNP2_2618 UCRNP2_4417 UCRNP2_5419 UCRNP2_5899 UCRNP2_6113 UCRNP2_7756 UCRNP2_803
TML: 
GSTUM_00008554001 GSTUM_00009484001
SPO: 
SPAC2E1P3.04(cao1) SPBC1289.16c(cao2)
CNE: 
CNG01110
CNB: 
CNBG3680
CGI: 
CGB_D2000W CGB_G5250W
TMS: 
TREMEDRAFT_64863
TVS: 
TRAVEDRAFT_155351 TRAVEDRAFT_171833
DSQ: 
DICSQDRAFT_85414 DICSQDRAFT_93162
PCO: 
PHACADRAFT_206924 PHACADRAFT_262981
SHS: 
STEHIDRAFT_132379 STEHIDRAFT_169602 STEHIDRAFT_75722
HIR: 
HETIRDRAFT_460901
PSQ: 
PUNSTDRAFT_54222 PUNSTDRAFT_96477
ADL: 
AURDEDRAFT_115401 AURDEDRAFT_72211
FME: 
FOMMEDRAFT_126935
GTR: 
GLOTRDRAFT_122375 GLOTRDRAFT_91048
MPR: 
MPER_07393
MRR: 
Moror_12827 Moror_2333 Moror_6708
CCI: 
CC1G_00597 CC1G_06947 CC1G_07935 CC1G_07936 CC1G_11177
SCM: 
SCHCODRAFT_255523 SCHCODRAFT_62890
ABP: 
AGABI1DRAFT110804(AGABI1DRAFT_110804) AGABI1DRAFT31353(AGABI1DRAFT_31353)
ABV: 
AGABI2DRAFT113718(AGABI2DRAFT_113718) AGABI2DRAFT196562(AGABI2DRAFT_196562) AGABI2DRAFT213491(AGABI2DRAFT_213491)
CPUT: 
CONPUDRAFT_130739 CONPUDRAFT_46458
SLA: 
SERLADRAFT_367597 SERLADRAFT_418714
WSE: 
WALSEDRAFT_16517 WALSEDRAFT_42854 WALSEDRAFT_59349
WIC: 
J056_001596 J056_001609 J056_004783
UMA: 
UMAG_03524
PFP: 
PFL1_05913
PGR: 
PGTG_11426
MLR: 
MELLADRAFT_37685
SMIN: 
v1.2.024444.t1(symbB.v1.2.024444.t1) v1.2.036815.t1(symbB.v1.2.036815.t1) v1.2.036815.t2(symbB.v1.2.036815.t2) v1.2.036815.t3(symbB.v1.2.036815.t3) v1.2.036815.t4(symbB.v1.2.036815.t4)
EHX: 
EMIHUDRAFT_197391 EMIHUDRAFT_205572 EMIHUDRAFT_220023 EMIHUDRAFT_242812
ECO: 
b1386(tynA)
ECJ: 
JW1381(tynA)
ECD: 
ECDH10B_1511(tynA)
EBW: 
BWG_1215(tynA)
EOJ: 
ECO26_1990(tynA)
EOI: 
ECO111_1780(tynA)
EOH: 
ECO103_1523(tynA)
ECX: 
EcHS_A1473(tynA)
ECW: 
EcE24377A_1571(tynA)
ECY: 
ECSE_1471
ECR: 
ECIAI1_1386(tynA)
ECK: 
EC55989_1522(tynA)
ELH: 
ETEC_1461
ESO: 
O3O_12090(tynA)
ESM: 
O3M_13515(tynA)
ESL: 
O3K_13540(tynA)
ECL: 
EcolC_2269
EBR: 
ECB_01358(tynA)
EKO: 
EKO11_2427
EKF: 
KO11_15190(tynA)
EDH: 
EcDH1_2259
EDJ: 
ECDH1ME8569_1331(tynA)
EUN: 
UMNK88_1793
ELW: 
ECW_m1520(tynA)
ELL: 
WFL_07425(tynA)
ELP: 
P12B_c1740(tynA)
EBL: 
ECD_01358(tynA)
ECOA: 
APECO78_10665(tynA)
ECOL: 
LY180_07250(tynA)
ECOO: 
ECRM13514_2000(tynA)
ECOH: 
ECRM13516_1753(tynA)
EFE: 
EFER_1611(tynA)
SHQ: 
A0259_11045(tynA)
ENC: 
ECL_02157
ENO: 
ECENHK_10295(tynA)
EEC: 
EcWSU1_02051(tynA)
ENL: 
A3UG_10315(tynA)
ECLG: 
EC036_20040
ECLE: 
ECNIH2_10890(tynA)
ECLN: 
ECNIH4_12430(tynA)
ECLI: 
ECNIH5_11735(tynA)
ECLX: 
LI66_10230(tynA)
ECLY: 
LI62_11030(tynA)
ECLZ: 
LI64_10380(tynA)
ECLA: 
ECNIH3_10055(tynA)
ECLC: 
ECR091_10025(tynA)
ESC: 
Entcl_2424
KLE: 
AO703_10115(tynA)
EAS: 
Entas_2024
EAU: 
DI57_08545(tynA)
EHM: 
AB284_14780(tynA)
EKB: 
BFV64_10660(tynA)
ELG: 
BH714_06510(tynA)
EXF: 
BFV63_10415(tynA)
ECLS: 
LI67_015505(tynA)
ENX: 
NI40_010420(tynA)
KPN: 
KPN_01467(tynA)
KPU: 
KP1_2469(tynA)
KPM: 
KPHS_23670
KPP: 
A79E_2773
KPK: 
A593_21840(tynA)
KPH: 
KPNIH24_16380(tynA)
KPZ: 
KPNIH27_11540(tynA)
KPV: 
KPNIH29_11765(tynA)
KPW: 
KPNIH30_12305(tynA)
KPY: 
KPNIH31_11390(tynA)
KPG: 
KPNIH32_12145(tynA)
KPC: 
KPNIH10_11850(tynA)
KPQ: 
KPR0928_11860(tynA)
KPT: 
VK055_1043(maoA)
KPE: 
KPK_3002(tynA)
KPO: 
KPN2242_10115(tynA)
KPR: 
KPR_2876(maoA)
KPI: 
D364_07185(tynA)
KPA: 
KPNJ1_03031
KPS: 
KPNJ2_03031
KPX: 
PMK1_03785(maoA)
KPB: 
FH42_03230(tynA)
KPNE: 
KU54_014355(tynA)
KPNU: 
LI86_14290(tynA)
KVA: 
Kvar_2900
KVD: 
KR75_19660(tynA)
KVQ: 
SP68_00700(tynA)
KOX: 
KOX_19410(tynA)
KOE: 
A225_2752
KOY: 
J415_18220(tynA)
KMI: 
VW41_11840(tynA)
KOK: 
KONIH1_13480(tynA)
KOC: 
AB185_21610(tynA)
KOM: 
HR38_17740(tynA)
KQU: 
AVR78_16375(tynA)
EAE: 
EAE_20530(tynA)
EAR: 
CCG29775
EBT: 
EBL_c16540(tynA)
ROR: 
RORB6_07560(tynA)
RON: 
TE10_12980(tynA)
CNT: 
JT31_00450(tynA)
CEM: 
LH23_16445(tynA)
CEN: 
LH86_15435(tynA)
PGE: 
LG71_17870(tynA)
LAX: 
APT61_10015(tynA)
LAZ: 
A8A57_10295
EBF: 
D782_2334
SFW: 
WN53_13885(tynA)
SFG: 
AV650_09435(tynA)
HAV: 
AT03_19260(tynA)
OPO: 
DSM2777_06135(tynA)
PPI: 
YSA_08839
PPSY: 
AOC04_06075(tynA)
PSPG: 
AK823_04885(tynA)
PSYG: 
AK825_04900(tynA)
ACB: 
A1S_1854
ABY: 
ABAYE1710(tynA)
ABC: 
ACICU_01966
ABN: 
AB57_2189
ABB: 
ABBFA_001598
ABX: 
ABK1_2433
ABZ: 
ABZJ_02147
ABR: 
ABTJ_01742
ABD: 
ABTW07_2178
ABH: 
M3Q_2314
ABAD: 
ABD1_18770
ABJ: 
BJAB07104_01773
ABAB: 
BJAB0715_02112
ABAJ: 
BJAB0868_02105
ABAZ: 
P795_7480
ABK: 
LX00_09950(tynA)
ABAA: 
IX88_11450(tynA)
ABW: 
BL01_00770(tynA)
ABAL: 
ABLAC_27290
ACC: 
BDGL_001334(tynA)
ACD: 
AOLE_08570(tynA)
ACW: 
A0J50_07930(tynA)
LPN: 
lpg2910(tynA)
LPH: 
LPV_3277(tynA)
LPO: 
LPO_3228(tynA)
LPU: 
LPE509_00105
LPM: 
LP6_2945(tynA)
LPP: 
lpp2979
LPC: 
LPC_3213(tynA)
LPA: 
lpa_04254(tynA)
LPE: 
lp12_2898
RSN: 
RSPO_m00628(tynA)
BPY: 
Bphyt_1997
BFN: 
OI25_3600
HSE: 
Hsero_3531(tynA)
HSZ: 
ACP92_17605(tynA)
HRB: 
Hrubri_2912(tynA)
SUR: 
STAUR_3973
MLO: 
mll6250
SIX: 
BSY16_3732
ARA: 
Arad_9757
ATF: 
Ach5_50140(tynA)
RLE: 
RL3036
SHZ: 
shn_15985
BJU: 
BJ6T_52360
BJP: 
RN69_25505(tynA)
BRA: 
BRADO6525
BBT: 
BBta_1115
BRS: 
S23_36690 S23_45520
BRC: 
BCCGELA001_19020(tynA)
BIC: 
LMTR13_34190(tynA)
RPB: 
RPB_1133
HMC: 
HYPMC_0415(maoI)
PSF: 
PSE_p0337
PPHR: 
APZ00_11310
YAN: 
AYJ57_20290
APK: 
APA386B_241(tynA)
TMO: 
TMO_3343(maoI)
BACI: 
B1NLA3E_18970(tynA)
PJD: 
Pjdr2_0710 Pjdr2_3546
PSAB: 
PSAB_02300(tynA)
PDU: 
PDUR_11695(tynA)
PBJ: 
VN24_01135(tynA)
PNP: 
IJ22_08160
MSM: 
MSMEG_2526(tynA) MSMEG_3847(tynA)
MSG: 
MSMEI_2467 MSMEI_3757
MSB: 
LJ00_12575(tynA) LJ00_19110
MSN: 
LI99_12575(tynA) LI99_19115
MSH: 
LI98_12580(tynA) LI98_19120
MSA: 
Mycsm_02367 Mycsm_03689 Mycsm_05412
MVA: 
Mvan_2218 Mvan_3407
MGI: 
Mflv_3126 Mflv_4125
MSP: 
Mspyr1_24430 Mspyr1_34680
MAB: 
MAB_4204
MABB: 
MASS_4239(tynA)
MMV: 
MYCMA_04515
MAY: 
LA62_21370
MABO: 
NF82_21060
MABL: 
MMASJCM_4290
MAZ: 
LA61_21265
MAK: 
LH56_03165
MYS: 
NF92_03220
MYC: 
NF90_03220
MCHE: 
BB28_21655
MIZ: 
BAB75_24075
MMC: 
Mmcs_2000
MKM: 
Mkms_2046
MJL: 
Mjls_1981
MMI: 
MMAR_2608(maoX)
MMAE: 
MMARE11_25280(maoX)
MCB: 
Mycch_3038
MNE: 
D174_26550
MYV: 
G155_17470
MYE: 
AB431_10905(tynA)
MGO: 
AFA91_12450 AFA91_20820 AFA91_26910(tynA)
MFT: 
XA26_35610
MPHL: 
MPHLCCUG_02168(maoII)
MVQ: 
MYVA_2137(tynA1) MYVA_3313(tynA2)
CGY: 
CGLY_12535
NFA: 
NFA_27860
NFR: 
ERS450000_01309
NSL: 
BOX37_13200
RHA: 
RHA1_ro02608 RHA1_ro02834 RHA1_ro05597 RHA1_ro08476(maoA)
ROP: 
ROP_23340 ROP_25580 ROP_56620
ROA: 
Pd630_LPD02195 Pd630_LPD06835 Pd630_LPD06996
RHB: 
NY08_107 NY08_4048 NY08_4668
RAV: 
AAT18_02345
RFA: 
A3L23_02739(maoII)
GPO: 
GPOL_c04840 GPOL_c10670 GPOL_c33260
GTA: 
BCM27_04725 BCM27_04955
SMA: 
SAV_2149
SVL: 
Strvi_2346 Strvi_5193
SCT: 
SCAT_5049
SCY: 
SCATT_50430
SBH: 
SBI_01422(tynA) SBI_03047
SHY: 
SHJG_7164 SHJG_8672
SHO: 
SHJGH_6924 SHJGH_8432
SVE: 
SVEN_5900
SDV: 
BN159_2258
SCI: 
B446_28565
SRC: 
M271_14090 M271_46705 M271_50510
SGU: 
SGLAU_26165
SVT: 
SVTN_29490
SCW: 
TU94_03770(tynA) TU94_26070
SLD: 
T261_6537
SXI: 
SXIM_30490
STRC: 
AA958_06970
SCX: 
AS200_11865
SRW: 
TUE45_06711(maoII)
SLE: 
sle_15920(sle_15920)
SLC: 
SL103_25890
SGS: 
AVL59_12030
STSI: 
A4E84_31285
SLS: 
SLINC_6562
MTS: 
MTES_0658 MTES_2618
MIM: 
AKG07_00430
MIO: 
AOA12_05855
MIP: 
AXH82_11470
MIH: 
BJP65_05075
MVD: 
AWU67_11270
FRP: 
AX769_11170(tynA)
AGY: 
ATC03_00980 ATC03_14675
CART: 
PA27867_1452 PA27867_3477
ART: 
Arth_3502
ARR: 
ARUE_c05480 ARUE_c37570
ARI: 
UM93_06890
ARL: 
AFL94_13410
ARE: 
AL755_02220(tynA) AL755_03955 AL755_05495 AL755_13940 AL755_14060(tynA)
AAQ: 
AOC05_17530
ARH: 
AHiyo8_05480
ARY: 
ATC04_04555
ARW: 
MB46_07035
AAU: 
AAur_0579 AAur_1378(maoII) AAur_pTC20082 AAur_pTC20192
ACH: 
Achl_3572
PSUL: 
AU252_12820(tynA)
AAI: 
AARI_26060
GAR: 
AOZ07_13440 AOZ07_15570 AOZ07_16685
SATK: 
SA2016_2484 SA2016_3857
BRX: 
BH708_14250
XCE: 
Xcel_3066
BLY: 
A2T55_03850
BLIN: 
BLSMQ_0725
MPH: 
MLP_35100
AER: 
AERYTH_06335
SRO: 
Sros_8167
NOA: 
BKM31_30940 BKM31_31400
FRE: 
Franean1_7247
FRI: 
FraEuI1c_0778
NML: 
Namu_4963
GOB: 
Gobs_1742 Gobs_1923
BSD: 
BLASA_3513
MMAR: 
MODMU_2097(maoI) MODMU_4206
AOI: 
AORI_3584(tynA)
AJA: 
AJAP_21205
AMQ: 
AMETH_1325 AMETH_2730
ALU: 
BB31_04495
PDX: 
Psed_3749 Psed_6426
PSEE: 
FRP1_08235 FRP1_16400
PSEQ: 
AD006_15795 AD006_24050
PECQ: 
AD017_03640 AD017_23635
PHH: 
AFB00_02095
SESP: 
BN6_34440
ALL: 
CRK57855
MAU: 
Micau_2495
MIL: 
ML5_5868
ASE: 
ACPL_3926(tynA)
ACTN: 
L083_3311 L083_5454(tynA)
AFS: 
AFR_19155
CAI: 
Caci_2627
RRD: 
RradSPS_0331 RradSPS_3071
CWO: 
Cwoe_3876
CYA: 
CYA_1346
CYB: 
CYB_2794
SYNE: 
Syn6312_1679
LET: 
O77CONTIG1_02108(maoII)
GLP: 
Glo7428_0163
CYN: 
Cyan7425_1871
TER: 
Tery_1383
ANA: 
alr3431
NPU: 
Npun_R4934
NOS: 
Nos7107_2452
NOP: 
Nos7524_4552
NON: 
NOS3756_51710(tynA)
AVA: 
Ava_3451
ANB: 
ANA_C12068(tynA)
ACY: 
Anacy_5055
CSG: 
Cylst_6183
CALO: 
Cal7507_4635
CTHE: 
Chro_3560
HAU: 
Haur_3112
STI: 
Sthe_2982
GES: 
VT84_32830(maoII)
PBOR: 
BSF38_03571(maoII_1) BSF38_05460(maoII_2)
TSA: 
AciPR4_0473
SUS: 
Acid_0916 Acid_6105
ABAC: 
LuPra_06110(maoA)
GPH: 
GEMMAAP_02600
GBA: 
J421_1449
HJE: 
HacjB3_18513(tynA) HacjB3_18623(tynA)
NMO: 
Nmlp_3583
NOU: 
Natoc_0595 Natoc_1202 Natoc_1215
SSO: 
SSO1692(tynA)
SOL: 
Ssol_2477
SSOA: 
SULA_2500(tynA)
SSOL: 
SULB_2503(tynA)
SSOF: 
SULC_2498(tynA)
SAI: 
Saci_2182(tynA)
SACN: 
SacN8_10625(tynA)
SACR: 
SacRon12I_10875(tynA)
SACS: 
SUSAZ_09980
SIS: 
LS215_2856
SII: 
LD85_3011
SIH: 
SiH_2646
 » show all
Taxonomy
Reference
1  [PMID:7337701]
  Authors
Haywood GW, Large PJ.
  Title
Microbial oxidation of amines. Distribution, purification and properties of two primary-amine oxidases from the yeast Candida boidinii grown on amines as sole nitrogen source.
  Journal
Biochem. J. 199 (1981) 187-201.
Reference
2  [PMID:7622512]
  Authors
Tipping AJ, McPherson MJ.
  Title
Cloning and molecular analysis of the pea seedling copper amine oxidase.
  Journal
J. Biol. Chem. 270 (1995) 16939-46.
  Sequence
Reference
3  [PMID:8920635]
  Authors
Lyles GA.
  Title
Mammalian plasma and tissue-bound semicarbazide-sensitive amine oxidases: biochemical, pharmacological and toxicological aspects.
  Journal
Int. J. Biochem. Cell. Biol. 28 (1996) 259-74.
Reference
4  [PMID:9405045]
  Authors
Wilce MC, Dooley DM, Freeman HC, Guss JM, Matsunami H, McIntire WS, Ruggiero CE, Tanizawa K, Yamaguchi H.
  Title
Crystal structures of the copper-containing amine oxidase from Arthrobacter globiformis in the holo and apo forms: implications for the biogenesis of topaquinone.
  Journal
Biochemistry. 36 (1997) 16116-33.
  Sequence
Reference
5  [PMID:9677370]
  Authors
Lee Y, Sayre LM.
  Title
Reaffirmation that metabolism of polyamines by bovine plasma amine oxidase occurs strictly at the primary amino termini.
  Journal
J. Biol. Chem. 273 (1998) 19490-4.
Reference
6  [PMID:10668504]
  Authors
Houen G.
  Title
Mammalian Cu-containing amine oxidases (CAOs): new methods of analysis, structural relationships, and possible functions.
  Journal
APMIS. Suppl. 96 (1999) 1-46.
Reference
7  [PMID:11156689]
  Authors
Andres N, Lizcano JM, Rodriguez MJ, Romera M, Unzeta M, Mahy N.
  Title
Tissue activity and cellular localization of human semicarbazide-sensitive amine oxidase.
  Journal
J. Histochem. Cytochem. 49 (2001) 209-17.
Reference
8  [PMID:11985492]
  Authors
Saysell CG, Tambyrajah WS, Murray JM, Wilmot CM, Phillips SE, McPherson MJ, Knowles PF.
  Title
Probing the catalytic mechanism of Escherichia coli amine oxidase using mutational variants and a reversible inhibitor as a substrate analogue.
  Journal
Biochem. J. 365 (2002) 809-16.
Reference
9  [PMID:14697905]
  Authors
O'Sullivan J, Unzeta M, Healy J, O'Sullivan MI, Davey G, Tipton KF.
  Title
Semicarbazide-sensitive amine oxidases: enzymes with quite a lot to do.
  Journal
Neurotoxicology. 25 (2004) 303-15.
Reference
10 [PMID:16046623]
  Authors
Airenne TT, Nymalm Y, Kidron H, Smith DJ, Pihlavisto M, Salmi M, Jalkanen S, Johnson MS, Salminen TA.
  Title
Crystal structure of the human vascular adhesion protein-1: unique structural features with functional implications.
  Journal
Protein. Sci. 14 (2005) 1964-74.
  Sequence
[hsa:8639]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
DBGET integrated database retrieval system