KEGG   ENZYME: 1.4.3.24Help
Entry
EC 1.4.3.24                 Enzyme                                 

Name
pseudooxynicotine oxidase
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor
BRITE hierarchy
Sysname
4-(methylamino)-1-(pyridin-3-yl)butan-1-one:oxygen oxidoreductase (methylamine releasing)
Reaction(IUBMB)
4-(methylamino)-1-(pyridin-3-yl)butan-1-one + H2O + O2 = 4-oxo-4-(pyridin-3-yl)butanal + methylamine + H2O2 [RN:R10103]
Reaction(KEGG)
Substrate
4-(methylamino)-1-(pyridin-3-yl)butan-1-one [CPD:C20361];
H2O [CPD:C00001];
O2 [CPD:C00007]
Product
4-oxo-4-(pyridin-3-yl)butanal [CPD:C19567];
methylamine [CPD:C00218];
H2O2 [CPD:C00027]
Comment
Contains one non-covalently bound FAD molecule per dimer. This enzyme, characterized from the soil bacterium Pseudomonas sp. HZN6, is involved the nicotine degradation.
History
EC 1.4.3.24 created 2012
Reference
1  [PMID:22267672]
  Authors
Qiu J, Ma Y, Wen Y, Chen L, Wu L, Liu W
  Title
Functional identification of two novel genes from Pseudomonas sp. strain HZN6 involved in the catabolism of nicotine.
  Journal
Appl. Environ. Microbiol. 78 (2012) 2154-60.
  Organism
Pseudomonas sp.
  Sequence
[up:H8ZPX1]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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