KEGG   ENZYME: 1.5.1.22Help
Entry
EC 1.5.1.22                 Enzyme                                 

Name
strombine dehydrogenase;
strombine[N-(carboxymethyl)-D-alanine]dehydrogenase;
N-(carboxymethyl)-D-alanine: NAD+ oxidoreductase
Class
Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
N-(carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming)
Reaction(IUBMB)
N-(carboxymethyl)-D-alanine + NAD+ + H2O = glycine + pyruvate + NADH + H+ [RN:R00368]
Reaction(KEGG)
Substrate
N-(carboxymethyl)-D-alanine [CPD:C03790];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
glycine [CPD:C00037];
pyruvate [CPD:C00022];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Also catalyses the reaction of EC 1.5.1.17 alanopine dehydrogenase, but more slowly. Does not act on L-strombine.
History
EC 1.5.1.22 created 1986
Reference
1
  Authors
Dando, P.R.
  Title
Strombine [N-(carboxymethyl)-D-alanine] dehydrogenase and alanopine [meso-N-(1-carboxyethyl)-alanine dehydrogenase from the mussel Mytilus edulis L.
  Journal
Biochem. Soc. Trans. 9 (1981) 297-298.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
79393-84-3

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