KEGG   ENZYME: 1.5.1.23Help
Entry
EC 1.5.1.23                 Enzyme                                 

Name
tauropine dehydrogenase;
2-N-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)
Class
Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
N2-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)
Reaction(IUBMB)
tauropine + NAD+ + H2O = taurine + pyruvate + NADH + H+ [RN:R01683]
Reaction(KEGG)
Substrate
tauropine [CPD:C01616];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
taurine [CPD:C00245];
pyruvate [CPD:C00022];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
In the reverse reaction, alanine can act instead of taurine, but more slowly, and 2-oxobutanoate and 2-oxopentanoate can act instead of pyruvate.
History
EC 1.5.1.23 created 1989
Reference
1  [PMID:3769931]
  Authors
Gade G.
  Title
Purification and properties of tauropine dehydrogenase from the shell adductor muscle of the ormer, Haliotis lamellosa.
  Journal
Eur. J. Biochem. 160 (1986) 311-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
104645-74-1

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